2A7G

On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection Wavelength

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0004222	molecular_function	metalloendopeptidase activity
E	0006508	biological_process	proteolysis

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 401

Chain	Residue
E	HIS142
E	HIS146
E	GLU166
E	ACY408

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA E 402

Chain	Residue
E	HOH458
E	GLU177
E	ASN183
E	ASP185
E	GLU190
E	HOH449

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA E 403

Chain	Residue
E	ASP57
E	ASP59
E	GLN61
E	HOH443
E	HOH461
E	HOH476

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA E 404

Chain	Residue
E	ASP138
E	GLU177
E	ASP185
E	GLU187
E	GLU190
E	HOH434

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA E 405

Chain	Residue
E	TYR193
E	THR194
E	ILE197
E	ASP200
E	HOH414
E	HOH432

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA E 406

Chain	Residue
E	TYR211
E	HOH546
E	HOH584
E	HOH585
E	HOH586

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CA E 407

Chain	Residue
E	GLN108

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE DMS E 332

Chain	Residue
E	TYR66
E	HIS216
E	SER218
E	TYR251
E	HOH518

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE DMS E 333

Chain	Residue
E	PRO184
E	ASP185
E	TRP186
E	HOH462
E	HOH526

---

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ACY E 408

Chain	Residue
E	ALA113
E	HIS142
E	GLU143
E	HIS146
E	TYR157
E	GLU166
E	HIS231
E	ZN401

---

Functional Information from PROSITE/UniProt

site_id	PS00142
Number of Residues	10
Details	ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VVAHELTHAV

Chain	Residue	Details
E	VAL139-VAL148

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"4808703","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"4808703","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Binding site: {}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1tlp

Chain	Residue	Details
E	HIS231
E	GLU143

---

site_id	MCSA1
Number of Residues	7
Details	M-CSA 176

Chain

Residue

Details

---