Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 502 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU77 |
| A | GLU80 |
| A | HOH975 |
| A | HOH1215 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 503 |
| Chain | Residue |
| A | VAL75 |
| A | GLU77 |
| A | GLU80 |
| A | HOH975 |
| A | HOH1215 |
| A | GLU70 |
| A | ASN72 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 504 |
| Chain | Residue |
| A | HOH1115 |
| A | HOH1158 |
| A | HOH1159 |
| A | HOH1160 |
| A | HOH1161 |
| A | HOH1162 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 505 |
| Chain | Residue |
| A | HOH1138 |
| A | HOH1165 |
| A | HOH1167 |
| A | HOH1168 |
| A | HOH1169 |
| A | HOH1170 |
| A | HOH1233 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 506 |
| Chain | Residue |
| A | GLY78 |
| A | GLU80 |
| A | HOH944 |
| A | HOH1014 |
| A | HOH1151 |
| A | HOH1152 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 511 |
| Chain | Residue |
| A | ARG66 |
| A | HOH1009 |
| A | HOH1086 |
| A | HOH1179 |
| A | HOH1183 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BO4 A 901 |
| Chain | Residue |
| A | SER164 |
| A | SER167 |
| A | HOH1092 |
| A | HOH1234 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PG3 A 501 |
| Chain | Residue |
| A | HIS57 |
| A | SER127 |
| A | ASP189 |
| A | SER190 |
| A | CYS191 |
| A | GLN192 |
| A | SER195 |
| A | VAL213 |
| A | SER214 |
| A | TRP215 |
| A | GLY216 |
| A | GLY219 |
| A | GLY226 |
| A | HOH940 |
| A | HOH983 |
| A | HOH1067 |
| A | HOH1214 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE BO4 A 512 |
| Chain | Residue |
| A | SER37 |
| A | LYS60 |
| A | SER61 |
| A | ARG62 |
| A | SER164 |
| A | ASP165 |
| A | SER166 |
| A | HOH1011 |
| A | HOH1230 |
| A | HOH1235 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU70 | |
| A | ASN72 | |
| A | VAL75 | |
| A | GLU80 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Required for specificity => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP189 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP102 | |
| A | HIS57 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER195 | |
| A | GLY196 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER195 | |
| A | GLY193 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP102 | |
| A | SER195 | |
| A | HIS57 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP102 | |
| A | SER195 | |
| A | HIS57 | |
| A | GLY196 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP102 | |
| A | SER195 | |
| A | GLY193 | |
| A | HIS57 | |
