2A2I
Aquifex aeolicus KDO8PS in complex with PEP, A5P, Zn2+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| A | 0046364 | biological_process | monosaccharide biosynthetic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008676 | molecular_function | 3-deoxy-8-phosphooctulonate synthase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019294 | biological_process | keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| B | 0046364 | biological_process | monosaccharide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 1270 |
| Chain | Residue |
| A | CYS1011 |
| A | HIS1185 |
| A | GLU1222 |
| A | ASP1233 |
| A | A5P1269 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 2270 |
| Chain | Residue |
| B | A5P2269 |
| B | CYS2011 |
| B | HIS2185 |
| B | GLU2222 |
| B | ASP2233 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PEP A 1268 |
| Chain | Residue |
| A | LYS1041 |
| A | SER1043 |
| A | LYS1046 |
| A | GLN1099 |
| A | PRO1101 |
| A | ALA1102 |
| A | LYS1124 |
| A | ARG1154 |
| A | HIS1185 |
| A | PHE1220 |
| A | A5P1269 |
| A | HOH3017 |
| A | HOH3031 |
| A | HOH3088 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PEP B 2268 |
| Chain | Residue |
| B | LYS2041 |
| B | SER2043 |
| B | LYS2046 |
| B | ASP2081 |
| B | GLN2099 |
| B | PRO2101 |
| B | ALA2102 |
| B | LYS2124 |
| B | ARG2154 |
| B | HIS2185 |
| B | PHE2220 |
| B | A5P2269 |
| B | HOH3044 |
| B | HOH3051 |
| B | HOH3093 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE A5P A 1269 |
| Chain | Residue |
| A | ASN1048 |
| A | ARG1049 |
| A | SER1050 |
| A | ARG1154 |
| A | HIS1185 |
| A | GLN1188 |
| A | SER1197 |
| A | ASP1233 |
| A | PEP1268 |
| A | ZN1270 |
| A | HOH3017 |
| A | HOH3118 |
| B | ARG2106 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE A5P B 2269 |
| Chain | Residue |
| A | ARG1106 |
| B | LYS2046 |
| B | ASN2048 |
| B | ARG2049 |
| B | SER2050 |
| B | HIS2185 |
| B | SER2232 |
| B | ASP2233 |
| B | PEP2268 |
| B | ZN2270 |
| B | HOH3044 |
| B | HOH3055 |
| B | HOH3062 |
| B | HOH3840 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| A | HIS1185 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| B | HIS2185 |
