Functional Information from PROSITE/UniProt
| site_id | PS00608 |
| Number of Residues | 15 |
| Details | GLYCOSYL_HYDROL_F2_2 Glycosyl hydrolases family 2 acid/base catalyst. DRNHPSVIIWSlg.NE |
| Chain | Residue | Details |
| A | ASP448-GLU462 | |
| site_id | PS00719 |
| Number of Residues | 26 |
| Details | GLYCOSYL_HYDROL_F2_1 Glycosyl hydrolases family 2 signature 1. NaVRCSHYPnhplWYtlcDryGLYVV |
| Chain | Residue | Details |
| A | ASN386-VAL411 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"6420154","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"1350782","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 36 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11045615","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Site: {"description":"Transition state stabilizer"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important for ensuring that an appropriate proportion of lactose is converted to allolactose"} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 10 |
| Details | M-CSA 422 |
| Chain | Residue | Details |
| A | ASP202 | |
| A | ASN605 | |
| A | HIS358 | |
| A | HIS392 | |
| A | GLU417 | |
| A | HIS419 | |
| A | GLU462 | |
| A | GLU538 | |
| A | ASN598 | |
| A | PHE602 | |
| site_id | MCSA2 |
| Number of Residues | 10 |
| Details | M-CSA 422 |
| Chain | Residue | Details |
| B | ASP202 | |
| B | ASN605 | |
| B | HIS358 | |
| B | HIS392 | |
| B | GLU417 | |
| B | HIS419 | |
| B | GLU462 | |
| B | GLU538 | |
| B | ASN598 | |
| B | PHE602 | |
| site_id | MCSA3 |
| Number of Residues | 10 |
| Details | M-CSA 422 |
| Chain | Residue | Details |
| C | ASP202 | |
| C | ASN605 | |
| C | HIS358 | |
| C | HIS392 | |
| C | GLU417 | |
| C | HIS419 | |
| C | GLU462 | |
| C | GLU538 | |
| C | ASN598 | |
| C | PHE602 | |
| site_id | MCSA4 |
| Number of Residues | 10 |
| Details | M-CSA 422 |
| Chain | Residue | Details |
| D | ASP202 | |
| D | ASN605 | |
| D | HIS358 | |
| D | HIS392 | |
| D | GLU417 | |
| D | HIS419 | |
| D | GLU462 | |
| D | GLU538 | |
| D | ASN598 | |
| D | PHE602 | |
28YO
