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28XA

Cryo-EM structure of the human UAP56 NTD - LENG8-PCID2-SEM1 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0006974biological_processDNA damage response
A0008643biological_processcarbohydrate transport
A0015768biological_processmaltose transport
A0016020cellular_componentmembrane
A0030288cellular_componentouter membrane-bounded periplasmic space
A0034219biological_processcarbohydrate transmembrane transport
A0034289biological_processdetection of maltose stimulus
A0042597cellular_componentperiplasmic space
A0042956biological_processmaltodextrin transmembrane transport
A0043190cellular_componentATP-binding cassette (ABC) transporter complex
A0055052cellular_componentATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A0060326biological_processcell chemotaxis
A1901982molecular_functionmaltose binding
A1990060cellular_componentmaltose transport complex
B0000973biological_processpost-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
B0003690molecular_functiondouble-stranded DNA binding
B0003723molecular_functionRNA binding
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005643cellular_componentnuclear pore
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0006368biological_processtranscription elongation by RNA polymerase II
B0006406biological_processmRNA export from nucleus
B0016973biological_processpoly(A)+ mRNA export from nucleus
B0032991cellular_componentprotein-containing complex
B0044615cellular_componentnuclear pore nuclear basket
B0045579biological_processpositive regulation of B cell differentiation
B0045814biological_processnegative regulation of gene expression, epigenetic
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0048536biological_processspleen development
B0070390cellular_componenttranscription export complex 2
B1905457biological_processnegative regulation of lymphoid progenitor cell differentiation
C0000502cellular_componentproteasome complex
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005829cellular_componentcytosol
C0006406biological_processmRNA export from nucleus
C0006979biological_processresponse to oxidative stress
C0008021cellular_componentsynaptic vesicle
C0010498biological_processproteasomal protein catabolic process
C0032039cellular_componentintegrator complex
C0032991cellular_componentprotein-containing complex
C0043130molecular_functionubiquitin binding
C0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
C0045944biological_processpositive regulation of transcription by RNA polymerase II
C0061136biological_processregulation of proteasomal protein catabolic process
C0070390cellular_componenttranscription export complex 2
C0071357biological_processcellular response to type I interferon
H0000245biological_processspliceosomal complex assembly
H0000346cellular_componenttranscription export complex
H0000398biological_processmRNA splicing, via spliceosome
H0003723molecular_functionRNA binding
H0003724molecular_functionRNA helicase activity
H0003729molecular_functionmRNA binding
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005681cellular_componentspliceosomal complex
H0005687cellular_componentU4 snRNP
H0005688cellular_componentU6 snRNP
H0005737cellular_componentcytoplasm
H0006405biological_processRNA export from nucleus
H0006406biological_processmRNA export from nucleus
H0008186molecular_functionATP-dependent activity, acting on RNA
H0008380biological_processRNA splicing
H0016607cellular_componentnuclear speck
H0016887molecular_functionATP hydrolysis activity
H0017070molecular_functionU6 snRNA binding
H0030621molecular_functionU4 snRNA binding
H0042802molecular_functionidentical protein binding
H0043008molecular_functionATP-dependent protein binding
Functional Information from PROSITE/UniProt
site_idPS01037
Number of Residues18
DetailsSBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN
ChainResidueDetails
APRO220-ASN237

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues181
DetailsDomain: {"description":"PCI","evidences":[{"source":"PROSITE-ProRule","id":"PRU01185","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

258009

PDB entries from 2026-08-12

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