27ZV

Structure of mouse urate oxidase in the apo state

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004846	molecular_function	urate oxidase activity
A	0005739	cellular_component	mitochondrion
A	0005777	cellular_component	peroxisome
A	0005829	cellular_component	cytosol
A	0006144	biological_process	purine nucleobase metabolic process
A	0006145	biological_process	purine nucleobase catabolic process
A	0006147	biological_process	guanine catabolic process
A	0006148	biological_process	inosine catabolic process
A	0006149	biological_process	deoxyinosine catabolic process
A	0006154	biological_process	adenosine catabolic process
A	0006157	biological_process	deoxyadenosine catabolic process
A	0006161	biological_process	deoxyguanosine catabolic process
A	0006196	biological_process	AMP catabolic process
A	0006204	biological_process	IMP catabolic process
A	0009114	biological_process	hypoxanthine catabolic process
A	0009115	biological_process	xanthine catabolic process
A	0019628	biological_process	urate catabolic process
A	0046038	biological_process	GMP catabolic process
A	0046055	biological_process	dGMP catabolic process
A	0046059	biological_process	dAMP catabolic process
B	0004846	molecular_function	urate oxidase activity
B	0005739	cellular_component	mitochondrion
B	0005777	cellular_component	peroxisome
B	0005829	cellular_component	cytosol
B	0006144	biological_process	purine nucleobase metabolic process
B	0006145	biological_process	purine nucleobase catabolic process
B	0006147	biological_process	guanine catabolic process
B	0006148	biological_process	inosine catabolic process
B	0006149	biological_process	deoxyinosine catabolic process
B	0006154	biological_process	adenosine catabolic process
B	0006157	biological_process	deoxyadenosine catabolic process
B	0006161	biological_process	deoxyguanosine catabolic process
B	0006196	biological_process	AMP catabolic process
B	0006204	biological_process	IMP catabolic process
B	0009114	biological_process	hypoxanthine catabolic process
B	0009115	biological_process	xanthine catabolic process
B	0019628	biological_process	urate catabolic process
B	0046038	biological_process	GMP catabolic process
B	0046055	biological_process	dGMP catabolic process
B	0046059	biological_process	dAMP catabolic process
C	0004846	molecular_function	urate oxidase activity
C	0005739	cellular_component	mitochondrion
C	0005777	cellular_component	peroxisome
C	0005829	cellular_component	cytosol
C	0006144	biological_process	purine nucleobase metabolic process
C	0006145	biological_process	purine nucleobase catabolic process
C	0006147	biological_process	guanine catabolic process
C	0006148	biological_process	inosine catabolic process
C	0006149	biological_process	deoxyinosine catabolic process
C	0006154	biological_process	adenosine catabolic process
C	0006157	biological_process	deoxyadenosine catabolic process
C	0006161	biological_process	deoxyguanosine catabolic process
C	0006196	biological_process	AMP catabolic process
C	0006204	biological_process	IMP catabolic process
C	0009114	biological_process	hypoxanthine catabolic process
C	0009115	biological_process	xanthine catabolic process
C	0019628	biological_process	urate catabolic process
C	0046038	biological_process	GMP catabolic process
C	0046055	biological_process	dGMP catabolic process
C	0046059	biological_process	dAMP catabolic process
D	0004846	molecular_function	urate oxidase activity
D	0005739	cellular_component	mitochondrion
D	0005777	cellular_component	peroxisome
D	0005829	cellular_component	cytosol
D	0006144	biological_process	purine nucleobase metabolic process
D	0006145	biological_process	purine nucleobase catabolic process
D	0006147	biological_process	guanine catabolic process
D	0006148	biological_process	inosine catabolic process
D	0006149	biological_process	deoxyinosine catabolic process
D	0006154	biological_process	adenosine catabolic process
D	0006157	biological_process	deoxyadenosine catabolic process
D	0006161	biological_process	deoxyguanosine catabolic process
D	0006196	biological_process	AMP catabolic process
D	0006204	biological_process	IMP catabolic process
D	0009114	biological_process	hypoxanthine catabolic process
D	0009115	biological_process	xanthine catabolic process
D	0019628	biological_process	urate catabolic process
D	0046038	biological_process	GMP catabolic process
D	0046055	biological_process	dGMP catabolic process
D	0046059	biological_process	dAMP catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00366
Number of Residues	28
Details	URICASE Uricase signature. LkVLKTTqSgFegFlkdqFttLpevkdR

Chain	Residue	Details
A	LEU160-ARG187

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"D0VWQ1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q00511","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	32
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"23576753","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17208939","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17242355","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---