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24MC

Structure of oocyte cytoplasmic lattices

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
a0000209biological_processprotein polyubiquitination
a0004842molecular_functionubiquitin-protein transferase activity
a0005515molecular_functionprotein binding
a0005737cellular_componentcytoplasm
a0005886cellular_componentplasma membrane
a0006511biological_processubiquitin-dependent protein catabolic process
a0006513biological_processprotein monoubiquitination
a0010008cellular_componentendosome membrane
a0016567biological_processprotein ubiquitination
a0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
a0051865biological_processprotein autoubiquitination
a0061631molecular_functionubiquitin conjugating enzyme activity
a0070936biological_processprotein K48-linked ubiquitination
a0070979biological_processprotein K11-linked ubiquitination
a0085020biological_processprotein K6-linked ubiquitination
A0001701biological_processin utero embryonic development
A0004668molecular_functionprotein-arginine deiminase activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0007010biological_processcytoskeleton organization
A0007028biological_processcytoplasm organization
A0008104biological_processintracellular protein localization
A0015631molecular_functiontubulin binding
A0040016biological_processembryonic cleavage
A0042802molecular_functionidentical protein binding
A0043143biological_processregulation of translation by machinery localization
A0044725biological_processepigenetic programming in the zygotic pronuclei
A0045111cellular_componentintermediate filament cytoskeleton
A0060473cellular_componentcortical granule
A0140089biological_processprotein storage
A0140094molecular_functionstructural constituent of cytoplasmic lattice
A0140095cellular_componentcytoplasmic lattice
A1990917cellular_componentooplasm
b0000122biological_processnegative regulation of transcription by RNA polymerase II
b0000785cellular_componentchromatin
b0000791cellular_componenteuchromatin
b0000792cellular_componentheterochromatin
b0000987molecular_functioncis-regulatory region sequence-specific DNA binding
b0003676molecular_functionnucleic acid binding
b0004842molecular_functionubiquitin-protein transferase activity
b0005515molecular_functionprotein binding
b0005634cellular_componentnucleus
b0005654cellular_componentnucleoplasm
b0005657cellular_componentreplication fork
b0005694cellular_componentchromosome
b0005829cellular_componentcytosol
b0006511biological_processubiquitin-dependent protein catabolic process
b0008270molecular_functionzinc ion binding
b0008327molecular_functionmethyl-CpG binding
b0016363cellular_componentnuclear matrix
b0016567biological_processprotein ubiquitination
b0031507biological_processheterochromatin formation
b0042393molecular_functionhistone binding
b0042802molecular_functionidentical protein binding
b0044027biological_processnegative regulation of gene expression via chromosomal CpG island methylation
b0044729molecular_functionhemi-methylated DNA-binding
b0045944biological_processpositive regulation of transcription by RNA polymerase II
b0050678biological_processregulation of epithelial cell proliferation
b0051247biological_processpositive regulation of protein metabolic process
b0051865biological_processprotein autoubiquitination
b0061630molecular_functionubiquitin protein ligase activity
b0062072molecular_functionhistone H3K9me2/3 reader activity
b0071168biological_processprotein localization to chromatin
b0090307biological_processmitotic spindle assembly
b0140006molecular_functionhistone H3 reader activity
b0140234molecular_functionhistone H3K23 ubiquitin ligase activity
b0140248molecular_functionhistone H3K18 ubiquitin ligase activity
b0140851molecular_functionhistone H3K14 ubiquitin ligase activity
b0141055molecular_functionhistone H3 ubiquitin ligase activity
b0141119biological_processchromosomal DNA methylation maintenance following DNA replication
B0001701biological_processin utero embryonic development
B0004668molecular_functionprotein-arginine deiminase activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0007010biological_processcytoskeleton organization
B0007028biological_processcytoplasm organization
B0008104biological_processintracellular protein localization
B0015631molecular_functiontubulin binding
B0040016biological_processembryonic cleavage
B0042802molecular_functionidentical protein binding
B0043143biological_processregulation of translation by machinery localization
B0044725biological_processepigenetic programming in the zygotic pronuclei
B0045111cellular_componentintermediate filament cytoskeleton
B0060473cellular_componentcortical granule
B0140089biological_processprotein storage
B0140094molecular_functionstructural constituent of cytoplasmic lattice
B0140095cellular_componentcytoplasmic lattice
B1990917cellular_componentooplasm
c0000209biological_processprotein polyubiquitination
c0004842molecular_functionubiquitin-protein transferase activity
c0005515molecular_functionprotein binding
c0005737cellular_componentcytoplasm
c0005886cellular_componentplasma membrane
c0006511biological_processubiquitin-dependent protein catabolic process
c0006513biological_processprotein monoubiquitination
c0010008cellular_componentendosome membrane
c0016567biological_processprotein ubiquitination
c0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
c0051865biological_processprotein autoubiquitination
c0061631molecular_functionubiquitin conjugating enzyme activity
c0070936biological_processprotein K48-linked ubiquitination
c0070979biological_processprotein K11-linked ubiquitination
c0085020biological_processprotein K6-linked ubiquitination
C0001701biological_processin utero embryonic development
C0004668molecular_functionprotein-arginine deiminase activity
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0007010biological_processcytoskeleton organization
C0007028biological_processcytoplasm organization
C0008104biological_processintracellular protein localization
C0015631molecular_functiontubulin binding
C0040016biological_processembryonic cleavage
C0042802molecular_functionidentical protein binding
C0043143biological_processregulation of translation by machinery localization
C0044725biological_processepigenetic programming in the zygotic pronuclei
C0045111cellular_componentintermediate filament cytoskeleton
C0060473cellular_componentcortical granule
C0140089biological_processprotein storage
C0140094molecular_functionstructural constituent of cytoplasmic lattice
C0140095cellular_componentcytoplasmic lattice
C1990917cellular_componentooplasm
d0000122biological_processnegative regulation of transcription by RNA polymerase II
d0000785cellular_componentchromatin
d0000791cellular_componenteuchromatin
d0000792cellular_componentheterochromatin
d0000987molecular_functioncis-regulatory region sequence-specific DNA binding
d0003676molecular_functionnucleic acid binding
d0004842molecular_functionubiquitin-protein transferase activity
d0005515molecular_functionprotein binding
d0005634cellular_componentnucleus
d0005654cellular_componentnucleoplasm
d0005657cellular_componentreplication fork
d0005694cellular_componentchromosome
d0005829cellular_componentcytosol
d0006511biological_processubiquitin-dependent protein catabolic process
d0008270molecular_functionzinc ion binding
d0008327molecular_functionmethyl-CpG binding
d0016363cellular_componentnuclear matrix
d0016567biological_processprotein ubiquitination
d0031507biological_processheterochromatin formation
d0042393molecular_functionhistone binding
d0042802molecular_functionidentical protein binding
d0044027biological_processnegative regulation of gene expression via chromosomal CpG island methylation
d0044729molecular_functionhemi-methylated DNA-binding
d0045944biological_processpositive regulation of transcription by RNA polymerase II
d0050678biological_processregulation of epithelial cell proliferation
d0051247biological_processpositive regulation of protein metabolic process
d0051865biological_processprotein autoubiquitination
d0061630molecular_functionubiquitin protein ligase activity
d0062072molecular_functionhistone H3K9me2/3 reader activity
d0071168biological_processprotein localization to chromatin
d0090307biological_processmitotic spindle assembly
d0140006molecular_functionhistone H3 reader activity
d0140234molecular_functionhistone H3K23 ubiquitin ligase activity
d0140248molecular_functionhistone H3K18 ubiquitin ligase activity
d0140851molecular_functionhistone H3K14 ubiquitin ligase activity
d0141055molecular_functionhistone H3 ubiquitin ligase activity
d0141119biological_processchromosomal DNA methylation maintenance following DNA replication
D0001701biological_processin utero embryonic development
D0004668molecular_functionprotein-arginine deiminase activity
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0007010biological_processcytoskeleton organization
D0007028biological_processcytoplasm organization
D0008104biological_processintracellular protein localization
D0015631molecular_functiontubulin binding
D0040016biological_processembryonic cleavage
D0042802molecular_functionidentical protein binding
D0043143biological_processregulation of translation by machinery localization
D0044725biological_processepigenetic programming in the zygotic pronuclei
D0045111cellular_componentintermediate filament cytoskeleton
D0060473cellular_componentcortical granule
D0140089biological_processprotein storage
D0140094molecular_functionstructural constituent of cytoplasmic lattice
D0140095cellular_componentcytoplasmic lattice
D1990917cellular_componentooplasm
e0003674molecular_functionmolecular_function
e0005575cellular_componentcellular_component
e0005737cellular_componentcytoplasm
e0007283biological_processspermatogenesis
e0050727biological_processregulation of inflammatory response
E0001701biological_processin utero embryonic development
E0004668molecular_functionprotein-arginine deiminase activity
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005737cellular_componentcytoplasm
E0007010biological_processcytoskeleton organization
E0007028biological_processcytoplasm organization
E0008104biological_processintracellular protein localization
E0015631molecular_functiontubulin binding
E0040016biological_processembryonic cleavage
E0042802molecular_functionidentical protein binding
E0043143biological_processregulation of translation by machinery localization
E0044725biological_processepigenetic programming in the zygotic pronuclei
E0045111cellular_componentintermediate filament cytoskeleton
E0060473cellular_componentcortical granule
E0140089biological_processprotein storage
E0140094molecular_functionstructural constituent of cytoplasmic lattice
E0140095cellular_componentcytoplasmic lattice
E1990917cellular_componentooplasm
f0003674molecular_functionmolecular_function
f0005575cellular_componentcellular_component
f0005737cellular_componentcytoplasm
f0007283biological_processspermatogenesis
f0050727biological_processregulation of inflammatory response
F0001701biological_processin utero embryonic development
F0004668molecular_functionprotein-arginine deiminase activity
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005737cellular_componentcytoplasm
F0007010biological_processcytoskeleton organization
F0007028biological_processcytoplasm organization
F0008104biological_processintracellular protein localization
F0015631molecular_functiontubulin binding
F0040016biological_processembryonic cleavage
F0042802molecular_functionidentical protein binding
F0043143biological_processregulation of translation by machinery localization
F0044725biological_processepigenetic programming in the zygotic pronuclei
F0045111cellular_componentintermediate filament cytoskeleton
F0060473cellular_componentcortical granule
F0140089biological_processprotein storage
F0140094molecular_functionstructural constituent of cytoplasmic lattice
F0140095cellular_componentcytoplasmic lattice
F1990917cellular_componentooplasm
G0001701biological_processin utero embryonic development
G0004668molecular_functionprotein-arginine deiminase activity
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005737cellular_componentcytoplasm
G0007010biological_processcytoskeleton organization
G0007028biological_processcytoplasm organization
G0008104biological_processintracellular protein localization
G0015631molecular_functiontubulin binding
G0040016biological_processembryonic cleavage
G0042802molecular_functionidentical protein binding
G0043143biological_processregulation of translation by machinery localization
G0044725biological_processepigenetic programming in the zygotic pronuclei
G0045111cellular_componentintermediate filament cytoskeleton
G0060473cellular_componentcortical granule
G0140089biological_processprotein storage
G0140094molecular_functionstructural constituent of cytoplasmic lattice
G0140095cellular_componentcytoplasmic lattice
G1990917cellular_componentooplasm
h0000209biological_processprotein polyubiquitination
h0000775cellular_componentchromosome, centromeric region
h0004842molecular_functionubiquitin-protein transferase activity
h0005515molecular_functionprotein binding
h0005634cellular_componentnucleus
h0005654cellular_componentnucleoplasm
h0005737cellular_componentcytoplasm
h0005813cellular_componentcentrosome
h0005829cellular_componentcytosol
h0005921cellular_componentgap junction
h0006338biological_processchromatin remodeling
h0006511biological_processubiquitin-dependent protein catabolic process
h0006513biological_processprotein monoubiquitination
h0006915biological_processapoptotic process
h0007129biological_processhomologous chromosome pairing at meiosis
h0008013molecular_functionbeta-catenin binding
h0016567biological_processprotein ubiquitination
h0019005cellular_componentSCF ubiquitin ligase complex
h0019904molecular_functionprotein domain specific binding
h0031146biological_processSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
h0031467cellular_componentCul7-RING ubiquitin ligase complex
h0031519cellular_componentPcG protein complex
h0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
h0051457biological_processmaintenance of protein location in nucleus
h0070936biological_processprotein K48-linked ubiquitination
h0097602molecular_functioncullin family protein binding
h0140677molecular_functionmolecular function activator activity
h0160072molecular_functionubiquitin ligase complex scaffold activity
h1904037biological_processpositive regulation of epithelial cell apoptotic process
h1990444molecular_functionF-box domain binding
h1990756molecular_functionubiquitin-like ligase-substrate adaptor activity
h1990757molecular_functionubiquitin ligase activator activity
H0001701biological_processin utero embryonic development
H0004668molecular_functionprotein-arginine deiminase activity
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005737cellular_componentcytoplasm
H0007010biological_processcytoskeleton organization
H0007028biological_processcytoplasm organization
H0008104biological_processintracellular protein localization
H0015631molecular_functiontubulin binding
H0040016biological_processembryonic cleavage
H0042802molecular_functionidentical protein binding
H0043143biological_processregulation of translation by machinery localization
H0044725biological_processepigenetic programming in the zygotic pronuclei
H0045111cellular_componentintermediate filament cytoskeleton
H0060473cellular_componentcortical granule
H0140089biological_processprotein storage
H0140094molecular_functionstructural constituent of cytoplasmic lattice
H0140095cellular_componentcytoplasmic lattice
H1990917cellular_componentooplasm
I0001701biological_processin utero embryonic development
I0004668molecular_functionprotein-arginine deiminase activity
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005737cellular_componentcytoplasm
I0007010biological_processcytoskeleton organization
I0007028biological_processcytoplasm organization
I0008104biological_processintracellular protein localization
I0015631molecular_functiontubulin binding
I0040016biological_processembryonic cleavage
I0042802molecular_functionidentical protein binding
I0043143biological_processregulation of translation by machinery localization
I0044725biological_processepigenetic programming in the zygotic pronuclei
I0045111cellular_componentintermediate filament cytoskeleton
I0060473cellular_componentcortical granule
I0140089biological_processprotein storage
I0140094molecular_functionstructural constituent of cytoplasmic lattice
I0140095cellular_componentcytoplasmic lattice
I1990917cellular_componentooplasm
j0000209biological_processprotein polyubiquitination
j0000775cellular_componentchromosome, centromeric region
j0004842molecular_functionubiquitin-protein transferase activity
j0005515molecular_functionprotein binding
j0005634cellular_componentnucleus
j0005654cellular_componentnucleoplasm
j0005737cellular_componentcytoplasm
j0005813cellular_componentcentrosome
j0005829cellular_componentcytosol
j0005921cellular_componentgap junction
j0006338biological_processchromatin remodeling
j0006511biological_processubiquitin-dependent protein catabolic process
j0006513biological_processprotein monoubiquitination
j0006915biological_processapoptotic process
j0007129biological_processhomologous chromosome pairing at meiosis
j0008013molecular_functionbeta-catenin binding
j0016567biological_processprotein ubiquitination
j0019005cellular_componentSCF ubiquitin ligase complex
j0019904molecular_functionprotein domain specific binding
j0031146biological_processSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
j0031467cellular_componentCul7-RING ubiquitin ligase complex
j0031519cellular_componentPcG protein complex
j0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
j0051457biological_processmaintenance of protein location in nucleus
j0070936biological_processprotein K48-linked ubiquitination
j0097602molecular_functioncullin family protein binding
j0140677molecular_functionmolecular function activator activity
j0160072molecular_functionubiquitin ligase complex scaffold activity
j1904037biological_processpositive regulation of epithelial cell apoptotic process
j1990444molecular_functionF-box domain binding
j1990756molecular_functionubiquitin-like ligase-substrate adaptor activity
j1990757molecular_functionubiquitin ligase activator activity
K0001701biological_processin utero embryonic development
K0004668molecular_functionprotein-arginine deiminase activity
K0005515molecular_functionprotein binding
K0005634cellular_componentnucleus
K0005737cellular_componentcytoplasm
K0007010biological_processcytoskeleton organization
K0007028biological_processcytoplasm organization
K0008104biological_processintracellular protein localization
K0015631molecular_functiontubulin binding
K0040016biological_processembryonic cleavage
K0042802molecular_functionidentical protein binding
K0043143biological_processregulation of translation by machinery localization
K0044725biological_processepigenetic programming in the zygotic pronuclei
K0045111cellular_componentintermediate filament cytoskeleton
K0060473cellular_componentcortical granule
K0140089biological_processprotein storage
K0140094molecular_functionstructural constituent of cytoplasmic lattice
K0140095cellular_componentcytoplasmic lattice
K1990917cellular_componentooplasm
l0000209biological_processprotein polyubiquitination
l0000775cellular_componentchromosome, centromeric region
l0004842molecular_functionubiquitin-protein transferase activity
l0005515molecular_functionprotein binding
l0005634cellular_componentnucleus
l0005654cellular_componentnucleoplasm
l0005737cellular_componentcytoplasm
l0005813cellular_componentcentrosome
l0005829cellular_componentcytosol
l0005921cellular_componentgap junction
l0006338biological_processchromatin remodeling
l0006511biological_processubiquitin-dependent protein catabolic process
l0006513biological_processprotein monoubiquitination
l0006915biological_processapoptotic process
l0007129biological_processhomologous chromosome pairing at meiosis
l0008013molecular_functionbeta-catenin binding
l0016567biological_processprotein ubiquitination
l0019005cellular_componentSCF ubiquitin ligase complex
l0019904molecular_functionprotein domain specific binding
l0031146biological_processSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
l0031467cellular_componentCul7-RING ubiquitin ligase complex
l0031519cellular_componentPcG protein complex
l0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
l0051457biological_processmaintenance of protein location in nucleus
l0070936biological_processprotein K48-linked ubiquitination
l0097602molecular_functioncullin family protein binding
l0140677molecular_functionmolecular function activator activity
l0160072molecular_functionubiquitin ligase complex scaffold activity
l1904037biological_processpositive regulation of epithelial cell apoptotic process
l1990444molecular_functionF-box domain binding
l1990756molecular_functionubiquitin-like ligase-substrate adaptor activity
l1990757molecular_functionubiquitin ligase activator activity
m0003674molecular_functionmolecular_function
m0005575cellular_componentcellular_component
m0005737cellular_componentcytoplasm
m0008150biological_processbiological_process
M0000166molecular_functionnucleotide binding
M0005524molecular_functionATP binding
n0003674molecular_functionmolecular_function
n0005575cellular_componentcellular_component
n0005737cellular_componentcytoplasm
n0008150biological_processbiological_process
N0001701biological_processin utero embryonic development
N0003723molecular_functionRNA binding
N0005515molecular_functionprotein binding
N0005634cellular_componentnucleus
N0005737cellular_componentcytoplasm
N0005938cellular_componentcell cortex
N0006468biological_processprotein phosphorylation
N0007015biological_processactin filament organization
N0007566biological_processembryo implantation
N0009566biological_processfertilization
N0009880biological_processembryonic pattern specification
N0031297biological_processreplication fork processing
N0032880biological_processregulation of protein localization
N0032991cellular_componentprotein-containing complex
N0035088biological_processestablishment or maintenance of apical/basal cell polarity
N0045177cellular_componentapical part of cell
N0045836biological_processpositive regulation of meiotic nuclear division
N0051293biological_processestablishment of spindle localization
N0051302biological_processregulation of cell division
N0065003biological_processprotein-containing complex assembly
N0070201biological_processregulation of establishment of protein localization
N0106333cellular_componentsubcortical maternal complex
N0140089biological_processprotein storage
N0140094molecular_functionstructural constituent of cytoplasmic lattice
N0140095cellular_componentcytoplasmic lattice
N1905168biological_processpositive regulation of double-strand break repair via homologous recombination
N2000781biological_processpositive regulation of double-strand break repair
p0003674molecular_functionmolecular_function
p0005575cellular_componentcellular_component
p0005737cellular_componentcytoplasm
p0008150biological_processbiological_process
P0001701biological_processin utero embryonic development
P0005515molecular_functionprotein binding
P0005634cellular_componentnucleus
P0005730cellular_componentnucleolus
P0005737cellular_componentcytoplasm
P0005739cellular_componentmitochondrion
P0005794cellular_componentGolgi apparatus
P0005829cellular_componentcytosol
P0005938cellular_componentcell cortex
P0006887biological_processexocytosis
P0007015biological_processactin filament organization
P0007566biological_processembryo implantation
P0008104biological_processintracellular protein localization
P0009566biological_processfertilization
P0009887biological_processanimal organ morphogenesis
P0015631molecular_functiontubulin binding
P0031647biological_processregulation of protein stability
P0032880biological_processregulation of protein localization
P0032991cellular_componentprotein-containing complex
P0040019biological_processpositive regulation of embryonic development
P0043487biological_processregulation of RNA stability
P0045179cellular_componentapical cortex
P0050727biological_processregulation of inflammatory response
P0051293biological_processestablishment of spindle localization
P0051302biological_processregulation of cell division
P0051656biological_processestablishment of organelle localization
P0060471biological_processcortical granule exocytosis
P0060473cellular_componentcortical granule
P0065003biological_processprotein-containing complex assembly
P0106333cellular_componentsubcortical maternal complex
P0140089biological_processprotein storage
P0140094molecular_functionstructural constituent of cytoplasmic lattice
P0140095cellular_componentcytoplasmic lattice
Q0000122biological_processnegative regulation of transcription by RNA polymerase II
Q0003714molecular_functiontranscription corepressor activity
Q0005515molecular_functionprotein binding
Q0005634cellular_componentnucleus
Q0005667cellular_componenttranscription regulator complex
Q0005737cellular_componentcytoplasm
Q0005829cellular_componentcytosol
Q0005938cellular_componentcell cortex
Q0007015biological_processactin filament organization
Q0007283biological_processspermatogenesis
Q0007284biological_processspermatogonial cell division
Q0030317biological_processflagellated sperm motility
Q0032502biological_processdevelopmental process
Q0032991cellular_componentprotein-containing complex
Q0040019biological_processpositive regulation of embryonic development
Q0044725biological_processepigenetic programming in the zygotic pronuclei
Q0045666biological_processpositive regulation of neuron differentiation
Q0050769biological_processpositive regulation of neurogenesis
Q0051293biological_processestablishment of spindle localization
Q0051302biological_processregulation of cell division
Q0051643biological_processendoplasmic reticulum localization
Q0051646biological_processmitochondrion localization
Q0060136biological_processembryonic process involved in female pregnancy
Q0090090biological_processnegative regulation of canonical Wnt signaling pathway
Q0097225cellular_componentsperm midpiece
Q0106333cellular_componentsubcortical maternal complex
Q0140089biological_processprotein storage
Q0140094molecular_functionstructural constituent of cytoplasmic lattice
Q0140095cellular_componentcytoplasmic lattice
R0000166molecular_functionnucleotide binding
R0005524molecular_functionATP binding
S0001701biological_processin utero embryonic development
S0005515molecular_functionprotein binding
S0005634cellular_componentnucleus
S0005730cellular_componentnucleolus
S0005737cellular_componentcytoplasm
S0005739cellular_componentmitochondrion
S0005794cellular_componentGolgi apparatus
S0005829cellular_componentcytosol
S0005938cellular_componentcell cortex
S0006887biological_processexocytosis
S0007015biological_processactin filament organization
S0007566biological_processembryo implantation
S0008104biological_processintracellular protein localization
S0009566biological_processfertilization
S0009887biological_processanimal organ morphogenesis
S0015631molecular_functiontubulin binding
S0031647biological_processregulation of protein stability
S0032880biological_processregulation of protein localization
S0032991cellular_componentprotein-containing complex
S0040019biological_processpositive regulation of embryonic development
S0043487biological_processregulation of RNA stability
S0045179cellular_componentapical cortex
S0050727biological_processregulation of inflammatory response
S0051293biological_processestablishment of spindle localization
S0051302biological_processregulation of cell division
S0051656biological_processestablishment of organelle localization
S0060471biological_processcortical granule exocytosis
S0060473cellular_componentcortical granule
S0065003biological_processprotein-containing complex assembly
S0106333cellular_componentsubcortical maternal complex
S0140089biological_processprotein storage
S0140094molecular_functionstructural constituent of cytoplasmic lattice
S0140095cellular_componentcytoplasmic lattice
T0000122biological_processnegative regulation of transcription by RNA polymerase II
T0003714molecular_functiontranscription corepressor activity
T0005515molecular_functionprotein binding
T0005634cellular_componentnucleus
T0005667cellular_componenttranscription regulator complex
T0005737cellular_componentcytoplasm
T0005829cellular_componentcytosol
T0005938cellular_componentcell cortex
T0007015biological_processactin filament organization
T0007283biological_processspermatogenesis
T0007284biological_processspermatogonial cell division
T0030317biological_processflagellated sperm motility
T0032502biological_processdevelopmental process
T0032991cellular_componentprotein-containing complex
T0040019biological_processpositive regulation of embryonic development
T0044725biological_processepigenetic programming in the zygotic pronuclei
T0045666biological_processpositive regulation of neuron differentiation
T0050769biological_processpositive regulation of neurogenesis
T0051293biological_processestablishment of spindle localization
T0051302biological_processregulation of cell division
T0051643biological_processendoplasmic reticulum localization
T0051646biological_processmitochondrion localization
T0060136biological_processembryonic process involved in female pregnancy
T0090090biological_processnegative regulation of canonical Wnt signaling pathway
T0097225cellular_componentsperm midpiece
T0106333cellular_componentsubcortical maternal complex
T0140089biological_processprotein storage
T0140094molecular_functionstructural constituent of cytoplasmic lattice
T0140095cellular_componentcytoplasmic lattice
U0001701biological_processin utero embryonic development
U0003723molecular_functionRNA binding
U0005515molecular_functionprotein binding
U0005634cellular_componentnucleus
U0005737cellular_componentcytoplasm
U0005938cellular_componentcell cortex
U0006468biological_processprotein phosphorylation
U0007015biological_processactin filament organization
U0007566biological_processembryo implantation
U0009566biological_processfertilization
U0009880biological_processembryonic pattern specification
U0031297biological_processreplication fork processing
U0032880biological_processregulation of protein localization
U0032991cellular_componentprotein-containing complex
U0035088biological_processestablishment or maintenance of apical/basal cell polarity
U0045177cellular_componentapical part of cell
U0045836biological_processpositive regulation of meiotic nuclear division
U0051293biological_processestablishment of spindle localization
U0051302biological_processregulation of cell division
U0065003biological_processprotein-containing complex assembly
U0070201biological_processregulation of establishment of protein localization
U0106333cellular_componentsubcortical maternal complex
U0140089biological_processprotein storage
U0140094molecular_functionstructural constituent of cytoplasmic lattice
U0140095cellular_componentcytoplasmic lattice
U1905168biological_processpositive regulation of double-strand break repair via homologous recombination
U2000781biological_processpositive regulation of double-strand break repair
V0000977molecular_functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
V0001933biological_processnegative regulation of protein phosphorylation
V0003700molecular_functionDNA-binding transcription factor activity
V0005515molecular_functionprotein binding
V0005576cellular_componentextracellular region
V0005634cellular_componentnucleus
V0005737cellular_componentcytoplasm
V0005829cellular_componentcytosol
V0007015biological_processactin filament organization
V0009749biological_processresponse to glucose
V0016020cellular_componentmembrane
V0032868biological_processresponse to insulin
V0040019biological_processpositive regulation of embryonic development
V0045944biological_processpositive regulation of transcription by RNA polymerase II
V0050821biological_processprotein stabilization
V0051293biological_processestablishment of spindle localization
V0051643biological_processendoplasmic reticulum localization
V0051646biological_processmitochondrion localization
V0090263biological_processpositive regulation of canonical Wnt signaling pathway
W0000226biological_processmicrotubule cytoskeleton organization
W0000278biological_processmitotic cell cycle
W0001764biological_processneuron migration
W0005200molecular_functionstructural constituent of cytoskeleton
W0005525molecular_functionGTP binding
W0005737cellular_componentcytoplasm
W0005856cellular_componentcytoskeleton
W0005874cellular_componentmicrotubule
W0005929cellular_componentcilium
W0015630cellular_componentmicrotubule cytoskeleton
W0021987biological_processcerebral cortex development
W0045171cellular_componentintercellular bridge
W0072686cellular_componentmitotic spindle
W0097228cellular_componentsperm principal piece
W0097229cellular_componentsperm end piece
W0097542cellular_componentciliary tip
X0000226biological_processmicrotubule cytoskeleton organization
X0000278biological_processmitotic cell cycle
X0003924molecular_functionGTPase activity
X0005200molecular_functionstructural constituent of cytoskeleton
X0005525molecular_functionGTP binding
X0005634cellular_componentnucleus
X0005737cellular_componentcytoplasm
X0005856cellular_componentcytoskeleton
X0005874cellular_componentmicrotubule
X0005881cellular_componentcytoplasmic microtubule
X0005929cellular_componentcilium
X0015630cellular_componentmicrotubule cytoskeleton
X0030182biological_processneuron differentiation
X0045121cellular_componentmembrane raft
Y0000226biological_processmicrotubule cytoskeleton organization
Y0000278biological_processmitotic cell cycle
Y0003924molecular_functionGTPase activity
Y0005200molecular_functionstructural constituent of cytoskeleton
Y0005525molecular_functionGTP binding
Y0005634cellular_componentnucleus
Y0005737cellular_componentcytoplasm
Y0005856cellular_componentcytoskeleton
Y0005874cellular_componentmicrotubule
Y0005881cellular_componentcytoplasmic microtubule
Y0005929cellular_componentcilium
Y0015630cellular_componentmicrotubule cytoskeleton
Y0030182biological_processneuron differentiation
Y0045121cellular_componentmembrane raft
Z0000226biological_processmicrotubule cytoskeleton organization
Z0000278biological_processmitotic cell cycle
Z0001764biological_processneuron migration
Z0005200molecular_functionstructural constituent of cytoskeleton
Z0005525molecular_functionGTP binding
Z0005737cellular_componentcytoplasm
Z0005856cellular_componentcytoskeleton
Z0005874cellular_componentmicrotubule
Z0005929cellular_componentcilium
Z0015630cellular_componentmicrotubule cytoskeleton
Z0021987biological_processcerebral cortex development
Z0045171cellular_componentintercellular bridge
Z0072686cellular_componentmitotic spindle
Z0097228cellular_componentsperm principal piece
Z0097229cellular_componentsperm end piece
Z0097542cellular_componentciliary tip
Functional Information from PROSITE/UniProt
site_idPS00183
Number of Residues16
DetailsUBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNInsn.GsICLdiL
ChainResidueDetails
aTYR74-LEU89

site_idPS00213
Number of Residues13
DetailsLIPOCALIN Lipocalin signature. DVRd.NIFGAWFEA
ChainResidueDetails
bASP138-ALA150

site_idPS00227
Number of Residues7
DetailsTUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG
ChainResidueDetails
WGLY140-GLY146
XGLY142-GLY148

site_idPS00228
Number of Residues4
DetailsTUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI
ChainResidueDetails
WMET1-ILE4

site_idPS00518
Number of Residues10
DetailsZF_RING_1 Zinc finger RING-type signature. CqHnVCkdCL
ChainResidueDetails
bCYS728-LEU737

site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. ALAGftDgTVRIWDL
ChainResidueDetails
QALA402-LEU416

site_idPS01359
Number of Residues62
DetailsZF_PHD_1 Zinc finger PHD-type signature. CrfCkddenkpcrkcachvcggreapekq....................LlCde..Cdma.FHlyClkppltsvppepe................................WyCpsC
ChainResidueDetails
bCYS307-CYS368

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI2
Number of Residues20
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q6TGC4","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues200
DetailsDomain: {"description":"KH; atypical"}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues1288
DetailsDomain: {"description":"NACHT","evidences":[{"source":"PROSITE-ProRule","id":"PRU00136","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues84
DetailsRepeat: {"description":"LRR 1"}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues82
DetailsRepeat: {"description":"LRR 2"}
ChainResidueDetails

site_idSWS_FT_FI8
Number of Residues80
DetailsRepeat: {"description":"LRR 3"}
ChainResidueDetails

site_idSWS_FT_FI9
Number of Residues80
DetailsRepeat: {"description":"LRR 4"}
ChainResidueDetails

site_idSWS_FT_FI10
Number of Residues80
DetailsRepeat: {"description":"LRR 5"}
ChainResidueDetails

site_idSWS_FT_FI11
Number of Residues82
DetailsRepeat: {"description":"LRR 6"}
ChainResidueDetails

site_idSWS_FT_FI12
Number of Residues82
DetailsRepeat: {"description":"LRR 7"}
ChainResidueDetails

site_idSWS_FT_FI13
Number of Residues84
DetailsRepeat: {"description":"LRR 8"}
ChainResidueDetails

site_idSWS_FT_FI14
Number of Residues82
DetailsRepeat: {"description":"LRR 9"}
ChainResidueDetails

site_idSWS_FT_FI15
Number of Residues42
DetailsRepeat: {"description":"LRR 10"}
ChainResidueDetails

site_idSWS_FT_FI16
Number of Residues42
DetailsRepeat: {"description":"LRR 11"}
ChainResidueDetails

site_idSWS_FT_FI17
Number of Residues28
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00136","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI18
Number of Residues76
DetailsRepeat: {"description":"WD 2"}
ChainResidueDetails

site_idSWS_FT_FI19
Number of Residues80
DetailsRepeat: {"description":"WD 3"}
ChainResidueDetails

site_idSWS_FT_FI20
Number of Residues80
DetailsRepeat: {"description":"WD 4"}
ChainResidueDetails

site_idSWS_FT_FI21
Number of Residues74
DetailsRepeat: {"description":"WD 5"}
ChainResidueDetails

site_idSWS_FT_FI22
Number of Residues78
DetailsRepeat: {"description":"WD 6"}
ChainResidueDetails

site_idSWS_FT_FI23
Number of Residues78
DetailsRepeat: {"description":"WD 7"}
ChainResidueDetails

site_idSWS_FT_FI24
Number of Residues62
DetailsRepeat: {"description":"WD 8"}
ChainResidueDetails

site_idSWS_FT_FI25
Number of Residues2
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9H808","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI26
Number of Residues6
DetailsMotif: {"description":"MREI motif","evidences":[{"source":"UniProtKB","id":"P07437","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI27
Number of Residues14
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"Q13509","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI28
Number of Residues18
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"P68363","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI29
Number of Residues2
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P99024","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI30
Number of Residues2
DetailsModified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P99024","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI31
Number of Residues2
DetailsModified residue: {"description":"Phosphoserine; by CDK1","evidences":[{"source":"UniProtKB","id":"Q13885","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI32
Number of Residues4
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P07437","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI33
Number of Residues2
DetailsModified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"UniProtKB","id":"P07437","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI34
Number of Residues2
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"UniProtKB","id":"P07437","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI35
Number of Residues4
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P07437","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI36
Number of Residues6
DetailsMotif: {"description":"MREC motif","evidences":[{"source":"UniProtKB","id":"P68363","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI37
Number of Residues2
DetailsActive site: {"evidences":[{"source":"UniProtKB","id":"P68363","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI38
Number of Residues2
DetailsModified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9BQE3","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI39
Number of Residues5
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI40
Number of Residues292
DetailsDomain: {"description":"UBC core","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI41
Number of Residues2
DetailsActive site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10133","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI42
Number of Residues324
DetailsDomain: {"description":"YDG","evidences":[{"source":"PROSITE-ProRule","id":"PRU00358","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI43
Number of Residues78
DetailsZinc finger: {"description":"RING-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00175","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI44
Number of Residues136
DetailsRegion: {"description":"Tudor-like 2"}
ChainResidueDetails

site_idSWS_FT_FI45
Number of Residues10
DetailsRegion: {"description":"Linker","evidences":[{"source":"UniProtKB","id":"Q96T88","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI46
Number of Residues12
DetailsRegion: {"description":"Histone H3R2me0 binding","evidences":[{"source":"UniProtKB","id":"Q96T88","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI47
Number of Residues2
DetailsRegion: {"description":"Required to promote base flipping","evidences":[{"source":"PubMed","id":"18772891","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI48
Number of Residues12
DetailsRegion: {"description":"Required for formation of a 5-methylcytosine-binding pocket"}
ChainResidueDetails

site_idSWS_FT_FI49
Number of Residues46
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"Q96T88","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI50
Number of Residues2
DetailsSite: {"description":"Histone H3K4me0 binding","evidences":[{"source":"UniProtKB","id":"Q96T88","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI51
Number of Residues4
DetailsSite: {"description":"Histone H3R2me0 binding","evidences":[{"source":"UniProtKB","id":"Q96T88","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI52
Number of Residues2
DetailsSite: {"description":"Required to confer preferential recognition of cytosine over thymine","evidences":[{"source":"UniProtKB","id":"Q96T88","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI53
Number of Residues2
DetailsSite: {"description":"Required to discriminate between hemimethylated DNA versus symmetrically methylated DNA"}
ChainResidueDetails

site_idSWS_FT_FI54
Number of Residues2
DetailsSite: {"description":"Required for affinity and specificity for 5-mCpG sequence"}
ChainResidueDetails

site_idSWS_FT_FI55
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q96T88","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI56
Number of Residues2
DetailsModified residue: {"description":"Phosphoserine; by PKA","evidences":[{"source":"UniProtKB","id":"Q96T88","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI57
Number of Residues2
DetailsModified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q96T88","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI58
Number of Residues2
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q7TPK1","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI59
Number of Residues4
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"UniProtKB","id":"Q96T88","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI60
Number of Residues118
DetailsRegion: {"description":"Interaction with the F-box domain of F-box proteins","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI61
Number of Residues3
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI62
Number of Residues6
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)","evidences":[{"source":"UniProtKB","id":"P63208","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

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PDB entries from 2026-07-22

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