22RQFunctional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005249 | molecular_function | voltage-gated potassium channel activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005516 | molecular_function | calmodulin binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007268 | biological_process | chemical synaptic transmission |
| A | 0008076 | cellular_component | voltage-gated potassium channel complex |
| A | 0022843 | molecular_function | voltage-gated monoatomic cation channel activity |
| A | 0033268 | cellular_component | node of Ranvier |
| A | 0043194 | cellular_component | axon initial segment |
| A | 0045202 | cellular_component | synapse |
| A | 0071805 | biological_process | potassium ion transmembrane transport |
| B | 0005249 | molecular_function | voltage-gated potassium channel activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005516 | molecular_function | calmodulin binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0007268 | biological_process | chemical synaptic transmission |
| B | 0008076 | cellular_component | voltage-gated potassium channel complex |
| B | 0022843 | molecular_function | voltage-gated monoatomic cation channel activity |
| B | 0033268 | cellular_component | node of Ranvier |
| B | 0043194 | cellular_component | axon initial segment |
| B | 0045202 | cellular_component | synapse |
| B | 0071805 | biological_process | potassium ion transmembrane transport |
| C | 0005249 | molecular_function | voltage-gated potassium channel activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005516 | molecular_function | calmodulin binding |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0007268 | biological_process | chemical synaptic transmission |
| C | 0008076 | cellular_component | voltage-gated potassium channel complex |
| C | 0022843 | molecular_function | voltage-gated monoatomic cation channel activity |
| C | 0033268 | cellular_component | node of Ranvier |
| C | 0043194 | cellular_component | axon initial segment |
| C | 0045202 | cellular_component | synapse |
| C | 0071805 | biological_process | potassium ion transmembrane transport |
| D | 0005249 | molecular_function | voltage-gated potassium channel activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005516 | molecular_function | calmodulin binding |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0007268 | biological_process | chemical synaptic transmission |
| D | 0008076 | cellular_component | voltage-gated potassium channel complex |
| D | 0022843 | molecular_function | voltage-gated monoatomic cation channel activity |
| D | 0033268 | cellular_component | node of Ranvier |
| D | 0043194 | cellular_component | axon initial segment |
| D | 0045202 | cellular_component | synapse |
| D | 0071805 | biological_process | potassium ion transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 88 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S1","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 76 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 84 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S2","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 112 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 76 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S3","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 72 |
| Details | Transmembrane: {"description":"Helical; Voltage-sensor; Name=Segment S4","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 100 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S5","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 48 |
| Details | Intramembrane: {"description":"Pore-forming; Name=Segment H5","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 104 |
| Details | Transmembrane: {"description":"Helical; Name=Segment S6","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 20 |
| Details | Motif: {"description":"Selectivity filter","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"16319223","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
