22RQ

Human KCNQ3-XEN1101 complex in the presence of PIP2

This is a non-PDB format compatible entry.

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	88
Details	Transmembrane: {"description":"Helical; Name=Segment S1","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	76
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	84
Details	Transmembrane: {"description":"Helical; Name=Segment S2","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	112
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	76
Details	Transmembrane: {"description":"Helical; Name=Segment S3","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	72
Details	Transmembrane: {"description":"Helical; Voltage-sensor; Name=Segment S4","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	100
Details	Transmembrane: {"description":"Helical; Name=Segment S5","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	48
Details	Intramembrane: {"description":"Pore-forming; Name=Segment H5","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	104
Details	Transmembrane: {"description":"Helical; Name=Segment S6","evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	20
Details	Motif: {"description":"Selectivity filter","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"O43526","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"16319223","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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