Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

21HR

CryoEM structural of taurocholic acid bound OST alpha/beta transporter

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	62
Details	Transmembrane: {"description":"Helical; Name=TM1","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	70
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	50
Details	Transmembrane: {"description":"Helical; Name=TM2","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	58
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	58
Details	Transmembrane: {"description":"Helical; Name=TM3","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	56
Details	Transmembrane: {"description":"Helical; Name=TM4","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	56
Details	Transmembrane: {"description":"Helical; Name=TM5","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	58
Details	Transmembrane: {"description":"Helical; Name=TM6","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	46
Details	Transmembrane: {"description":"Helical; Name=TM7","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	28
Details	Region: {"description":"Extracellular loop 1 (ECL1)","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	28
Details	Region: {"description":"Extracellular loop 2 (ECL2)","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	18
Details	Motif: {"description":"Cysteine-rich loop","evidences":[{"source":"PubMed","id":"41606314","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	2
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"41606314","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	2
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"41606314","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	6
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"41606314","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	4
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"41606314","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9LJH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	54
Details	Transmembrane: {"description":"Helical; Name=TM0","evidences":[{"source":"PubMed","id":"41606328","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9UNV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9UO2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)