21AK

Cryo-EM structure of the E. coli ArnA hexamer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0009103	biological_process	lipopolysaccharide biosynthetic process
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0016742	molecular_function	hydroxymethyl-, formyl- and related transferase activity
A	0032991	cellular_component	protein-containing complex
A	0033320	biological_process	UDP-D-xylose biosynthetic process
A	0042802	molecular_function	identical protein binding
A	0046493	biological_process	lipid A metabolic process
A	0046677	biological_process	response to antibiotic
A	0048040	molecular_function	UDP-glucuronate decarboxylase activity
A	0070403	molecular_function	NAD+ binding
A	0099618	molecular_function	UDP-glucuronate dehydrogenase activity
A	0099619	molecular_function	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
A	2001315	biological_process	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
B	0005515	molecular_function	protein binding
B	0009103	biological_process	lipopolysaccharide biosynthetic process
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0016742	molecular_function	hydroxymethyl-, formyl- and related transferase activity
B	0032991	cellular_component	protein-containing complex
B	0033320	biological_process	UDP-D-xylose biosynthetic process
B	0042802	molecular_function	identical protein binding
B	0046493	biological_process	lipid A metabolic process
B	0046677	biological_process	response to antibiotic
B	0048040	molecular_function	UDP-glucuronate decarboxylase activity
B	0070403	molecular_function	NAD+ binding
B	0099618	molecular_function	UDP-glucuronate dehydrogenase activity
B	0099619	molecular_function	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
B	2001315	biological_process	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
C	0005515	molecular_function	protein binding
C	0009103	biological_process	lipopolysaccharide biosynthetic process
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0016742	molecular_function	hydroxymethyl-, formyl- and related transferase activity
C	0032991	cellular_component	protein-containing complex
C	0033320	biological_process	UDP-D-xylose biosynthetic process
C	0042802	molecular_function	identical protein binding
C	0046493	biological_process	lipid A metabolic process
C	0046677	biological_process	response to antibiotic
C	0048040	molecular_function	UDP-glucuronate decarboxylase activity
C	0070403	molecular_function	NAD+ binding
C	0099618	molecular_function	UDP-glucuronate dehydrogenase activity
C	0099619	molecular_function	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
C	2001315	biological_process	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
D	0005515	molecular_function	protein binding
D	0009103	biological_process	lipopolysaccharide biosynthetic process
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0016742	molecular_function	hydroxymethyl-, formyl- and related transferase activity
D	0032991	cellular_component	protein-containing complex
D	0033320	biological_process	UDP-D-xylose biosynthetic process
D	0042802	molecular_function	identical protein binding
D	0046493	biological_process	lipid A metabolic process
D	0046677	biological_process	response to antibiotic
D	0048040	molecular_function	UDP-glucuronate decarboxylase activity
D	0070403	molecular_function	NAD+ binding
D	0099618	molecular_function	UDP-glucuronate dehydrogenase activity
D	0099619	molecular_function	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
D	2001315	biological_process	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
E	0005515	molecular_function	protein binding
E	0009103	biological_process	lipopolysaccharide biosynthetic process
E	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
E	0016742	molecular_function	hydroxymethyl-, formyl- and related transferase activity
E	0032991	cellular_component	protein-containing complex
E	0033320	biological_process	UDP-D-xylose biosynthetic process
E	0042802	molecular_function	identical protein binding
E	0046493	biological_process	lipid A metabolic process
E	0046677	biological_process	response to antibiotic
E	0048040	molecular_function	UDP-glucuronate decarboxylase activity
E	0070403	molecular_function	NAD+ binding
E	0099618	molecular_function	UDP-glucuronate dehydrogenase activity
E	0099619	molecular_function	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
E	2001315	biological_process	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
F	0005515	molecular_function	protein binding
F	0009103	biological_process	lipopolysaccharide biosynthetic process
F	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
F	0016742	molecular_function	hydroxymethyl-, formyl- and related transferase activity
F	0032991	cellular_component	protein-containing complex
F	0033320	biological_process	UDP-D-xylose biosynthetic process
F	0042802	molecular_function	identical protein binding
F	0046493	biological_process	lipid A metabolic process
F	0046677	biological_process	response to antibiotic
F	0048040	molecular_function	UDP-glucuronate decarboxylase activity
F	0070403	molecular_function	NAD+ binding
F	0099618	molecular_function	UDP-glucuronate dehydrogenase activity
F	0099619	molecular_function	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
F	2001315	biological_process	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
G	0005515	molecular_function	protein binding
G	0009103	biological_process	lipopolysaccharide biosynthetic process
G	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
G	0016742	molecular_function	hydroxymethyl-, formyl- and related transferase activity
G	0032991	cellular_component	protein-containing complex
G	0033320	biological_process	UDP-D-xylose biosynthetic process
G	0042802	molecular_function	identical protein binding
G	0046493	biological_process	lipid A metabolic process
G	0046677	biological_process	response to antibiotic
G	0048040	molecular_function	UDP-glucuronate decarboxylase activity
G	0070403	molecular_function	NAD+ binding
G	0099618	molecular_function	UDP-glucuronate dehydrogenase activity
G	0099619	molecular_function	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
G	2001315	biological_process	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
H	0005515	molecular_function	protein binding
H	0009103	biological_process	lipopolysaccharide biosynthetic process
H	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
H	0016742	molecular_function	hydroxymethyl-, formyl- and related transferase activity
H	0032991	cellular_component	protein-containing complex
H	0033320	biological_process	UDP-D-xylose biosynthetic process
H	0042802	molecular_function	identical protein binding
H	0046493	biological_process	lipid A metabolic process
H	0046677	biological_process	response to antibiotic
H	0048040	molecular_function	UDP-glucuronate decarboxylase activity
H	0070403	molecular_function	NAD+ binding
H	0099618	molecular_function	UDP-glucuronate dehydrogenase activity
H	0099619	molecular_function	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
H	2001315	biological_process	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
I	0005515	molecular_function	protein binding
I	0009103	biological_process	lipopolysaccharide biosynthetic process
I	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
I	0016742	molecular_function	hydroxymethyl-, formyl- and related transferase activity
I	0032991	cellular_component	protein-containing complex
I	0033320	biological_process	UDP-D-xylose biosynthetic process
I	0042802	molecular_function	identical protein binding
I	0046493	biological_process	lipid A metabolic process
I	0046677	biological_process	response to antibiotic
I	0048040	molecular_function	UDP-glucuronate decarboxylase activity
I	0070403	molecular_function	NAD+ binding
I	0099618	molecular_function	UDP-glucuronate dehydrogenase activity
I	0099619	molecular_function	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
I	2001315	biological_process	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
J	0005515	molecular_function	protein binding
J	0009103	biological_process	lipopolysaccharide biosynthetic process
J	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
J	0016742	molecular_function	hydroxymethyl-, formyl- and related transferase activity
J	0032991	cellular_component	protein-containing complex
J	0033320	biological_process	UDP-D-xylose biosynthetic process
J	0042802	molecular_function	identical protein binding
J	0046493	biological_process	lipid A metabolic process
J	0046677	biological_process	response to antibiotic
J	0048040	molecular_function	UDP-glucuronate decarboxylase activity
J	0070403	molecular_function	NAD+ binding
J	0099618	molecular_function	UDP-glucuronate dehydrogenase activity
J	0099619	molecular_function	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
J	2001315	biological_process	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
K	0005515	molecular_function	protein binding
K	0009103	biological_process	lipopolysaccharide biosynthetic process
K	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
K	0016742	molecular_function	hydroxymethyl-, formyl- and related transferase activity
K	0032991	cellular_component	protein-containing complex
K	0033320	biological_process	UDP-D-xylose biosynthetic process
K	0042802	molecular_function	identical protein binding
K	0046493	biological_process	lipid A metabolic process
K	0046677	biological_process	response to antibiotic
K	0048040	molecular_function	UDP-glucuronate decarboxylase activity
K	0070403	molecular_function	NAD+ binding
K	0099618	molecular_function	UDP-glucuronate dehydrogenase activity
K	0099619	molecular_function	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
K	2001315	biological_process	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process
L	0005515	molecular_function	protein binding
L	0009103	biological_process	lipopolysaccharide biosynthetic process
L	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
L	0016742	molecular_function	hydroxymethyl-, formyl- and related transferase activity
L	0032991	cellular_component	protein-containing complex
L	0033320	biological_process	UDP-D-xylose biosynthetic process
L	0042802	molecular_function	identical protein binding
L	0046493	biological_process	lipid A metabolic process
L	0046677	biological_process	response to antibiotic
L	0048040	molecular_function	UDP-glucuronate decarboxylase activity
L	0070403	molecular_function	NAD+ binding
L	0099618	molecular_function	UDP-glucuronate dehydrogenase activity
L	0099619	molecular_function	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
L	2001315	biological_process	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Proton donor; for formyltransferase activity"}

Chain

Residue

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site_id	SWS_FT_FI2
Number of Residues	138
Details	Binding site: {}

Chain

Residue

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site_id	SWS_FT_FI3
Number of Residues	6
Details	Site: {"description":"Transition state stabilizer"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	6
Details	Site: {"description":"Raises pKa of active site His"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	6
Details	Active site: {"description":"Proton acceptor; for decarboxylase activity"}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	6
Details	Active site: {"description":"Proton donor; for decarboxylase activity"}

Chain

Residue

Details

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