1ZW8
Solution structure of a ZAP1 zinc-responsive domain provides insights into metalloregulatory transcriptional repression in Saccharomyces cerevisiae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 66 |
| Chain | Residue |
| A | CYS5 |
| A | CYS10 |
| A | HIS23 |
| A | HIS28 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 67 |
| Chain | Residue |
| A | CYS42 |
| A | CYS47 |
| A | PHE49 |
| A | HIS60 |
| A | HIS65 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 25 |
| Details | Zinc finger: {"description":"C2H2-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 25 |
| Details | Zinc finger: {"description":"C2H2-type 2; atypical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 62 |
| Details | Region: {"description":"Zinc-responsive domain 2 (ZRD(AD2))","evidences":[{"source":"PubMed","id":"10899124","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"21177862","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9271382","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 29 |
| Details | Region: {"description":"Transcription activation domain 2 (AD2)","evidences":[{"source":"PubMed","id":"21177862","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16483601","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ZW8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
