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1ZV5

Crystal structure of the variable domain of the camelid heavy-chain antibody D2-L29 in complex with hen egg white lysozyme

Functional Information from GO Data
ChainGOidnamespacecontents
L0003796molecular_functionlysozyme activity
L0005515molecular_functionprotein binding
L0005576cellular_componentextracellular region
L0005615cellular_componentextracellular space
L0005737cellular_componentcytoplasm
L0005783cellular_componentendoplasmic reticulum
L0016231molecular_functionbeta-N-acetylglucosaminidase activity
L0016798molecular_functionhydrolase activity, acting on glycosyl bonds
L0016998biological_processcell wall macromolecule catabolic process
L0031640biological_processkilling of cells of another organism
L0042742biological_processdefense response to bacterium
L0042802molecular_functionidentical protein binding
L0050829biological_processdefense response to Gram-negative bacterium
L0050830biological_processdefense response to Gram-positive bacterium
L0051672biological_processobsolete catabolism by organism of cell wall peptidoglycan in other organism
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE PO4 A 131
ChainResidue
AASN52
AARG101
ATYR103
AGLY104
AHOH155
AHOH164
LHIS15
LASN93
LLYS96

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE PO4 A 132
ChainResidue
AGLN39
AASP44
AARG45
LARG45

Functional Information from PROSITE/UniProt
site_idPS00128
Number of Residues19
DetailsGLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC
ChainResidueDetails
LCYS76-CYS94

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE:
ChainResidueDetails
LGLU35
LASP52

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING:
ChainResidueDetails
LASP101

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 132l
ChainResidueDetails
LGLU35
LASP52

site_idMCSA1
Number of Residues6
DetailsM-CSA 203
ChainResidueDetails
LGLU35hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
LASN46
LASP48
LSER50
LASP52covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
LASN59

224004

PDB entries from 2024-08-21

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