1ZUD

Structure of ThiS-ThiF protein complex

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0000166	molecular_function	nucleotide binding
1	0004792	molecular_function	thiosulfate-cyanide sulfurtransferase activity
1	0005524	molecular_function	ATP binding
1	0005737	cellular_component	cytoplasm
1	0005829	cellular_component	cytosol
1	0008146	molecular_function	sulfotransferase activity
1	0008270	molecular_function	zinc ion binding
1	0008641	molecular_function	ubiquitin-like modifier activating enzyme activity
1	0009228	biological_process	thiamine biosynthetic process
1	0009229	biological_process	thiamine diphosphate biosynthetic process
1	0016740	molecular_function	transferase activity
1	0016779	molecular_function	nucleotidyltransferase activity
1	0042803	molecular_function	protein homodimerization activity
1	0046872	molecular_function	metal ion binding
1	0052837	biological_process	thiazole biosynthetic process
1	0070733	molecular_function	AMPylase activity
2	0000166	molecular_function	nucleotide binding
2	0009228	biological_process	thiamine biosynthetic process
2	0009229	biological_process	thiamine diphosphate biosynthetic process
2	0052837	biological_process	thiazole biosynthetic process
2	0097163	molecular_function	sulfur carrier activity
2	1902503	cellular_component	adenylyltransferase complex
3	0000166	molecular_function	nucleotide binding
3	0004792	molecular_function	thiosulfate-cyanide sulfurtransferase activity
3	0005524	molecular_function	ATP binding
3	0005737	cellular_component	cytoplasm
3	0005829	cellular_component	cytosol
3	0008146	molecular_function	sulfotransferase activity
3	0008270	molecular_function	zinc ion binding
3	0008641	molecular_function	ubiquitin-like modifier activating enzyme activity
3	0009228	biological_process	thiamine biosynthetic process
3	0009229	biological_process	thiamine diphosphate biosynthetic process
3	0016740	molecular_function	transferase activity
3	0016779	molecular_function	nucleotidyltransferase activity
3	0042803	molecular_function	protein homodimerization activity
3	0046872	molecular_function	metal ion binding
3	0052837	biological_process	thiazole biosynthetic process
3	0070733	molecular_function	AMPylase activity
4	0000166	molecular_function	nucleotide binding
4	0009228	biological_process	thiamine biosynthetic process
4	0009229	biological_process	thiamine diphosphate biosynthetic process
4	0052837	biological_process	thiazole biosynthetic process
4	0097163	molecular_function	sulfur carrier activity
4	1902503	cellular_component	adenylyltransferase complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN 1 501

Chain	Residue
1	CYS169
1	CYS172
1	CYS240
1	CYS243

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN 3 502

Chain	Residue
3	CYS169
3	CYS172
3	CYS240
3	CYS243

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA 3 601

Chain	Residue
1	ASP16
1	HOH704
3	LEU14
3	ASP16
3	HOH764
1	LEU14

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA 1 602

Chain	Residue
1	CYS243
1	HOH800
1	HOH801
1	HOH802
3	HOH772
3	HOH809
3	HOH810

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA 1 701

Chain	Residue
1	VAL116
1	ALA117
1	ALA119
1	THR144
1	HOH755
1	HOH757

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA 3 702

Chain	Residue
3	VAL116
3	ALA117
3	ALA119
3	THR144
3	HOH796
3	HOH808

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16388576","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Glycyl adenylate; alternate","evidences":[{"source":"PubMed","id":"9632726","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Cross-link: {"description":"Glycyl cysteine dithioester (Gly-Cys) (interchain with C-184 in ThiF); alternate"}

Chain

Residue

Details

---