1ZT2
Heterodimeric structure of the core primase.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000428 | cellular_component | DNA-directed RNA polymerase complex |
| A | 0003899 | molecular_function | DNA-directed RNA polymerase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006260 | biological_process | DNA replication |
| A | 0006269 | biological_process | DNA replication, synthesis of primer |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 1990077 | cellular_component | primosome complex |
| B | 0003899 | molecular_function | DNA-directed RNA polymerase activity |
| C | 0000428 | cellular_component | DNA-directed RNA polymerase complex |
| C | 0003899 | molecular_function | DNA-directed RNA polymerase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0006259 | biological_process | DNA metabolic process |
| C | 0006260 | biological_process | DNA replication |
| C | 0006269 | biological_process | DNA replication, synthesis of primer |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 1990077 | cellular_component | primosome complex |
| D | 0003899 | molecular_function | DNA-directed RNA polymerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 999 |
| Chain | Residue |
| A | CYS116 |
| A | CYS119 |
| A | CYS128 |
| A | ASP131 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 999 |
| Chain | Residue |
| C | CYS116 |
| C | CYS119 |
| C | CYS128 |
| C | ASP131 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1000 |
| Chain | Residue |
| A | ASN175 |
| A | ARG176 |
| A | HIS253 |
| A | SO41009 |
| A | SER173 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | LYS255 |
| A | ASN321 |
| A | SO41012 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 213 |
| Chain | Residue |
| B | HIS164 |
| B | LYS165 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1002 |
| Chain | Residue |
| A | ARG303 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1000 |
| Chain | Residue |
| A | LYS15 |
| A | ARG19 |
| C | SER55 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 214 |
| Chain | Residue |
| B | ARG95 |
| B | HIS99 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1001 |
| Chain | Residue |
| C | SER173 |
| C | ASN175 |
| C | ARG176 |
| C | HIS253 |
| C | SO41004 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1002 |
| Chain | Residue |
| A | ASN132 |
| C | LYS169 |
| C | ARG262 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1003 |
| Chain | Residue |
| C | ARG303 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 213 |
| Chain | Residue |
| D | ARG95 |
| D | TRP156 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 215 |
| Chain | Residue |
| B | SO4218 |
| C | ASN302 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1003 |
| Chain | Residue |
| A | LYS109 |
| A | SER215 |
| A | ASN217 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1004 |
| Chain | Residue |
| A | THR47 |
| A | TYR48 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1005 |
| Chain | Residue |
| A | ASP235 |
| A | GLN237 |
| A | ARG244 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1006 |
| Chain | Residue |
| A | THR289 |
| A | ARG303 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1004 |
| Chain | Residue |
| C | HIS179 |
| C | ARG247 |
| C | HIS253 |
| C | SO41001 |
| site_id | CC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1005 |
| Chain | Residue |
| C | ASN321 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 214 |
| Chain | Residue |
| D | GLU103 |
| D | LYS172 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1006 |
| Chain | Residue |
| A | SO41007 |
| C | SER56 |
| C | SER57 |
| C | GLU58 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1007 |
| Chain | Residue |
| A | GLY9 |
| A | GLN10 |
| C | SO41006 |
| site_id | CC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1007 |
| Chain | Residue |
| C | SER215 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1008 |
| Chain | Residue |
| C | ASN175 |
| C | ARG176 |
| C | LYS255 |
| C | ARG320 |
| site_id | CC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 216 |
| Chain | Residue |
| B | LYS130 |
| B | ARG132 |
| site_id | CC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1008 |
| Chain | Residue |
| A | LYS169 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1009 |
| Chain | Residue |
| A | ASP101 |
| A | HIS179 |
| A | ARG247 |
| A | SO41000 |
| site_id | DC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 217 |
| Chain | Residue |
| B | ARG132 |
| B | ILE133 |
| B | ILE134 |
| B | GLN135 |
| site_id | DC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1010 |
| Chain | Residue |
| A | SER56 |
| A | SER57 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 218 |
| Chain | Residue |
| B | PRO200 |
| B | GLU201 |
| B | SO4215 |
| C | LYS300 |
| site_id | DC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1010 |
| Chain | Residue |
| C | SER45 |
| C | ASP46 |
| C | THR47 |
| site_id | DC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 219 |
| Chain | Residue |
| B | ASN102 |
| B | GLU103 |
| B | LYS172 |
| site_id | DC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1011 |
| Chain | Residue |
| A | ALA122 |
| A | VAL123 |
| A | VAL124 |
| A | SER125 |
| site_id | DC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1011 |
| Chain | Residue |
| C | SER125 |
| C | GLU126 |
| site_id | DC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1012 |
| Chain | Residue |
| A | LYS255 |
| A | SO41001 |
| site_id | DC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1012 |
| Chain | Residue |
| C | ARG148 |
| C | CYS108 |
| C | LYS109 |
| site_id | EC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 215 |
| Chain | Residue |
| D | ILE199 |
| D | PRO200 |
| D | GLU201 |
| site_id | EC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1013 |
| Chain | Residue |
| C | LYS15 |
| C | ARG19 |
| site_id | EC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 220 |
| Chain | Residue |
| B | LYS81 |
| B | ARG84 |
| B | ARG85 |
| site_id | EC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1014 |
| Chain | Residue |
| C | CYS184 |
| C | TYR185 |
| C | GLY186 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00700","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16273105","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
