1ZSQ
Crystal Structure of MTMR2 in complex with phosphatidylinositol 3-phosphate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO A 1878 |
| Chain | Residue |
| A | HIS458 |
| A | HOH1040 |
| A | ARG463 |
| A | VAL464 |
| A | SER477 |
| A | PRO478 |
| A | VAL479 |
| A | PHE480 |
| A | LEU481 |
| A | LEU512 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1879 |
| Chain | Residue |
| A | ARG360 |
| A | ALA472 |
| A | HOH1086 |
| A | HOH1279 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1880 |
| Chain | Residue |
| A | LYS156 |
| A | TYR513 |
| A | HOH1033 |
| A | HOH1044 |
| A | HOH1225 |
| A | HOH1382 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1881 |
| Chain | Residue |
| A | VAL358 |
| A | SER362 |
| A | LYS365 |
| A | THR386 |
| A | HIS387 |
| A | HIS391 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE PIB A 3632 |
| Chain | Residue |
| A | ASN330 |
| A | LYS333 |
| A | ASN355 |
| A | ILE356 |
| A | SER417 |
| A | SER418 |
| A | ASP419 |
| A | GLY420 |
| A | TRP421 |
| A | ASP422 |
| A | ARG423 |
| A | ARG463 |
| A | GLU549 |
| A | HOH1002 |
| A | HOH1089 |
| A | HOH1141 |
| A | HOH3721 |
| A | HOH3758 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 375 |
| Details | Domain: {"description":"Myotubularin phosphatase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00669","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PubMed","id":"14690594","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16410353","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16410353","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1ZSQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16410353","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1ZVR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
