1ZR5
Crystal structure of the macro-domain of human core histone variant macroH2A1.2
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:A0A0D2UG83 |
| Chain | Residue | Details |
| B | SER276 | |
| B | GLY313 | |
| B | SER314 | |
| A | LEU227 | |
| A | SER276 | |
| A | GLY313 | |
| A | SER314 | |
| A | GLY315 | |
| A | ASN317 | |
| B | LEU227 | |
| B | GLY315 | |
| B | ASN317 | |
| B | GLU201 | |
| B | ILE202 | |
| A | GLU201 | |
| A | ILE202 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER168 | |
| B | SER168 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER171 | |
| B | SER171 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| B | THR176 | |
| A | THR176 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS321 | |
| B | LYS321 | |
| A | LYS165 | |
| A | LYS187 | |
| B | LYS165 | |
| B | LYS187 |
