1ZPD
PYRUVATE DECARBOXYLASE FROM ZYMOMONAS MOBILIS
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
A | 0003824 | molecular_function | catalytic activity |
A | 0004737 | molecular_function | pyruvate decarboxylase activity |
A | 0005829 | cellular_component | cytosol |
A | 0016831 | molecular_function | carboxy-lyase activity |
A | 0019752 | biological_process | carboxylic acid metabolic process |
A | 0030976 | molecular_function | thiamine pyrophosphate binding |
A | 0046872 | molecular_function | metal ion binding |
B | 0000287 | molecular_function | magnesium ion binding |
B | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
B | 0003824 | molecular_function | catalytic activity |
B | 0004737 | molecular_function | pyruvate decarboxylase activity |
B | 0005829 | cellular_component | cytosol |
B | 0016831 | molecular_function | carboxy-lyase activity |
B | 0019752 | biological_process | carboxylic acid metabolic process |
B | 0030976 | molecular_function | thiamine pyrophosphate binding |
B | 0046872 | molecular_function | metal ion binding |
E | 0000287 | molecular_function | magnesium ion binding |
E | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
E | 0003824 | molecular_function | catalytic activity |
E | 0004737 | molecular_function | pyruvate decarboxylase activity |
E | 0005829 | cellular_component | cytosol |
E | 0016831 | molecular_function | carboxy-lyase activity |
E | 0019752 | biological_process | carboxylic acid metabolic process |
E | 0030976 | molecular_function | thiamine pyrophosphate binding |
E | 0046872 | molecular_function | metal ion binding |
F | 0000287 | molecular_function | magnesium ion binding |
F | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
F | 0003824 | molecular_function | catalytic activity |
F | 0004737 | molecular_function | pyruvate decarboxylase activity |
F | 0005829 | cellular_component | cytosol |
F | 0016831 | molecular_function | carboxy-lyase activity |
F | 0019752 | biological_process | carboxylic acid metabolic process |
F | 0030976 | molecular_function | thiamine pyrophosphate binding |
F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG A 601 |
Chain | Residue |
A | ASP440 |
A | ASN467 |
A | GLY469 |
A | DPX600 |
A | HOH611 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG B 601 |
Chain | Residue |
B | HOH611 |
B | ASP440 |
B | ASN467 |
B | GLY469 |
B | DPX600 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG E 601 |
Chain | Residue |
E | ASP440 |
E | ASN467 |
E | GLY469 |
E | DPX600 |
E | HOH611 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG F 601 |
Chain | Residue |
F | ASP440 |
F | ASN467 |
F | GLY469 |
F | DPX600 |
F | HOH611 |
site_id | AC5 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE DPX A 600 |
Chain | Residue |
A | ASP390 |
A | GLY413 |
A | HIS414 |
A | ILE415 |
A | GLY439 |
A | ASP440 |
A | GLY441 |
A | SER442 |
A | ASN467 |
A | GLY469 |
A | TYR470 |
A | THR471 |
A | ILE472 |
A | GLU473 |
A | MG601 |
A | HOH611 |
A | HOH612 |
A | HOH769 |
A | HOH1256 |
B | ALA25 |
B | GLY26 |
B | GLU50 |
B | VAL75 |
B | HIS114 |
site_id | AC6 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE CIT A 610 |
Chain | Residue |
A | ARG310 |
A | ARG318 |
A | PRO320 |
A | SER321 |
A | HOH709 |
A | HOH746 |
A | HOH789 |
A | HOH1006 |
A | HOH1049 |
F | HIS150 |
F | LYS153 |
F | ARG157 |
site_id | AC7 |
Number of Residues | 23 |
Details | BINDING SITE FOR RESIDUE DPX B 600 |
Chain | Residue |
A | ALA25 |
A | GLY26 |
A | GLU50 |
A | VAL75 |
A | HIS114 |
B | ASP390 |
B | GLY413 |
B | HIS414 |
B | ILE415 |
B | GLY439 |
B | ASP440 |
B | GLY441 |
B | SER442 |
B | ASN467 |
B | GLY469 |
B | TYR470 |
B | THR471 |
B | ILE472 |
B | GLU473 |
B | MG601 |
B | HOH611 |
B | HOH612 |
B | HOH842 |
site_id | AC8 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE CIT B 610 |
Chain | Residue |
B | ARG310 |
B | ARG318 |
B | PRO320 |
B | SER321 |
B | HOH688 |
B | HOH782 |
B | HOH819 |
B | HOH861 |
B | HOH1111 |
E | HIS150 |
E | LYS153 |
E | ARG157 |
site_id | AC9 |
Number of Residues | 23 |
Details | BINDING SITE FOR RESIDUE DPX E 600 |
Chain | Residue |
E | ASN467 |
E | GLY469 |
E | TYR470 |
E | THR471 |
E | ILE472 |
E | GLU473 |
E | MG601 |
E | HOH611 |
E | HOH612 |
E | HOH874 |
F | ALA25 |
F | GLY26 |
F | GLU50 |
F | VAL75 |
F | HIS114 |
E | ASP390 |
E | GLY413 |
E | HIS414 |
E | ILE415 |
E | GLY439 |
E | ASP440 |
E | GLY441 |
E | SER442 |
site_id | BC1 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE CIT E 610 |
Chain | Residue |
B | HIS150 |
B | LYS153 |
B | ARG157 |
E | ARG310 |
E | ARG318 |
E | PRO320 |
E | SER321 |
E | HOH656 |
E | HOH814 |
E | HOH851 |
E | HOH894 |
E | HOH1113 |
site_id | BC2 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE DPX F 600 |
Chain | Residue |
E | ALA25 |
E | GLY26 |
E | GLU50 |
E | VAL75 |
E | HIS114 |
F | ASP390 |
F | GLY413 |
F | HIS414 |
F | ILE415 |
F | GLY439 |
F | ASP440 |
F | GLY441 |
F | SER442 |
F | ASN467 |
F | GLY469 |
F | TYR470 |
F | THR471 |
F | ILE472 |
F | GLU473 |
F | MG601 |
F | HOH611 |
F | HOH612 |
F | HOH943 |
F | HOH1240 |
site_id | BC3 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE CIT F 610 |
Chain | Residue |
A | HIS150 |
A | LYS153 |
A | ARG157 |
F | ARG310 |
F | ARG318 |
F | PRO320 |
F | SER321 |
F | HOH712 |
F | HOH793 |
F | HOH885 |
F | HOH920 |
F | HOH962 |
Functional Information from PROSITE/UniProt
site_id | PS00187 |
Number of Residues | 20 |
Details | TPP_ENZYMES Thiamine pyrophosphate enzymes signature. FGyavgaPerrnIlMvGDGS |
Chain | Residue | Details |
A | PHE423-SER442 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 12 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | ASP27 | |
F | ASP27 | |
F | HIS114 | |
F | GLU473 | |
A | HIS114 | |
A | GLU473 | |
B | ASP27 | |
B | HIS114 | |
B | GLU473 | |
E | ASP27 | |
E | HIS114 | |
E | GLU473 |
site_id | SWS_FT_FI2 |
Number of Residues | 16 |
Details | BINDING: |
Chain | Residue | Details |
A | GLU50 | |
E | ASP440 | |
E | ASN467 | |
E | GLY469 | |
F | GLU50 | |
F | ASP440 | |
F | ASN467 | |
F | GLY469 | |
A | ASP440 | |
A | ASN467 | |
A | GLY469 | |
B | GLU50 | |
B | ASP440 | |
B | ASN467 | |
B | GLY469 | |
E | GLU50 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
F | THR545 |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | THR545 |
site_id | CSA3 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | THR545 |
site_id | CSA4 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
E | THR545 |
site_id | CSA5 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | GLU473 | |
A | HIS113 | |
A | HIS114 | |
A | ASP27 |
site_id | CSA6 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | GLU473 | |
B | HIS113 | |
B | HIS114 | |
B | ASP27 |
site_id | CSA7 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
E | GLU473 | |
E | HIS113 | |
E | HIS114 | |
E | ASP27 |
site_id | CSA8 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
F | GLU473 | |
F | HIS113 | |
F | HIS114 | |
F | ASP27 |