1ZJ9
Structure of Mycobacterium tuberculosis NirA protein
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000103 | biological_process | sulfate assimilation |
| A | 0005829 | cellular_component | cytosol |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016002 | molecular_function | sulfite reductase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050311 | molecular_function | sulfite reductase (ferredoxin) activity |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 0000103 | biological_process | sulfate assimilation |
| B | 0005829 | cellular_component | cytosol |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0016002 | molecular_function | sulfite reductase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050311 | molecular_function | sulfite reductase (ferredoxin) activity |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 570 |
| Chain | Residue |
| A | ARG97 |
| A | ARG166 |
| A | LYS207 |
| A | SRM569 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 1570 |
| Chain | Residue |
| B | ARG97 |
| B | ARG166 |
| B | LYS207 |
| B | SRM1569 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SF4 A 556 |
| Chain | Residue |
| A | SER418 |
| A | CYS423 |
| A | SER426 |
| A | GLY462 |
| A | CYS463 |
| A | ASN465 |
| A | CYS467 |
| A | SRM569 |
| A | CYS417 |
| site_id | AC4 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE SRM A 569 |
| Chain | Residue |
| A | TYR69 |
| A | ARG97 |
| A | SER128 |
| A | ASP129 |
| A | ARG130 |
| A | ASN132 |
| A | GLN134 |
| A | HIS136 |
| A | ARG206 |
| A | LYS207 |
| A | LYS209 |
| A | ILE222 |
| A | GLY246 |
| A | LEU247 |
| A | SER248 |
| A | ARG290 |
| A | GLN379 |
| A | ALA416 |
| A | CYS417 |
| A | SER418 |
| A | PHE422 |
| A | CYS423 |
| A | LEU425 |
| A | ARG431 |
| A | ASN465 |
| A | SER466 |
| A | CYS467 |
| A | ARG469 |
| A | SF4556 |
| A | CL570 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SF4 B 1556 |
| Chain | Residue |
| B | CYS417 |
| B | SER418 |
| B | GLY419 |
| B | CYS423 |
| B | SER426 |
| B | GLY462 |
| B | CYS463 |
| B | CYS467 |
| site_id | AC6 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE SRM B 1569 |
| Chain | Residue |
| B | TYR69 |
| B | MET95 |
| B | ARG97 |
| B | SER128 |
| B | ASP129 |
| B | ARG130 |
| B | ASN132 |
| B | GLN134 |
| B | HIS136 |
| B | VAL167 |
| B | ARG206 |
| B | LYS207 |
| B | LYS209 |
| B | ILE222 |
| B | GLY246 |
| B | LEU247 |
| B | SER248 |
| B | ARG290 |
| B | GLN379 |
| B | ALA416 |
| B | CYS417 |
| B | SER418 |
| B | PHE422 |
| B | CYS423 |
| B | ARG431 |
| B | ASN465 |
| B | SER466 |
| B | CYS467 |
| B | ARG469 |
| B | CL1570 |
Functional Information from PROSITE/UniProt
| site_id | PS00365 |
| Number of Residues | 17 |
| Details | NIR_SIR Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. NGCpnsCariqiaDIGF |
| Chain | Residue | Details |
| A | ASN461-PHE477 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | HIS409 | |
| A | MET415 | |
| A | PRO455 | |
| B | HIS409 | |
| B | MET415 | |
| B | PRO455 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| A | ASN459 | |
| B | ASN459 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CROSSLNK: 3'-(S-cysteinyl)-tyrosine (Tyr-Cys) |
| Chain | Residue | Details |
| A | GLY61 | |
| A | VAL153 | |
| B | GLY61 | |
| B | VAL153 |
