Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1ZI7

Structure of truncated yeast oxysterol binding protein Osh4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0006665	biological_process	sphingolipid metabolic process
A	0006869	biological_process	lipid transport
A	0006887	biological_process	exocytosis
A	0006892	biological_process	post-Golgi vesicle-mediated transport
A	0006897	biological_process	endocytosis
A	0008142	molecular_function	oxysterol binding
A	0008289	molecular_function	lipid binding
A	0015248	molecular_function	obsolete sterol transporter activity
A	0015918	biological_process	sterol transport
A	0016020	cellular_component	membrane
A	0030011	biological_process	maintenance of cell polarity
A	0034727	biological_process	piecemeal microautophagy of the nucleus
A	0035621	biological_process	ER to Golgi ceramide transport
A	0070273	molecular_function	phosphatidylinositol-4-phosphate binding
A	0070300	molecular_function	phosphatidic acid binding
A	0120015	molecular_function	sterol transfer activity
B	0000139	cellular_component	Golgi membrane
B	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
B	0005737	cellular_component	cytoplasm
B	0005794	cellular_component	Golgi apparatus
B	0005829	cellular_component	cytosol
B	0006665	biological_process	sphingolipid metabolic process
B	0006869	biological_process	lipid transport
B	0006887	biological_process	exocytosis
B	0006892	biological_process	post-Golgi vesicle-mediated transport
B	0006897	biological_process	endocytosis
B	0008142	molecular_function	oxysterol binding
B	0008289	molecular_function	lipid binding
B	0015248	molecular_function	obsolete sterol transporter activity
B	0015918	biological_process	sterol transport
B	0016020	cellular_component	membrane
B	0030011	biological_process	maintenance of cell polarity
B	0034727	biological_process	piecemeal microautophagy of the nucleus
B	0035621	biological_process	ER to Golgi ceramide transport
B	0070273	molecular_function	phosphatidylinositol-4-phosphate binding
B	0070300	molecular_function	phosphatidic acid binding
B	0120015	molecular_function	sterol transfer activity
C	0000139	cellular_component	Golgi membrane
C	0005546	molecular_function	phosphatidylinositol-4,5-bisphosphate binding
C	0005737	cellular_component	cytoplasm
C	0005794	cellular_component	Golgi apparatus
C	0005829	cellular_component	cytosol
C	0006665	biological_process	sphingolipid metabolic process
C	0006869	biological_process	lipid transport
C	0006887	biological_process	exocytosis
C	0006892	biological_process	post-Golgi vesicle-mediated transport
C	0006897	biological_process	endocytosis
C	0008142	molecular_function	oxysterol binding
C	0008289	molecular_function	lipid binding
C	0015248	molecular_function	obsolete sterol transporter activity
C	0015918	biological_process	sterol transport
C	0016020	cellular_component	membrane
C	0030011	biological_process	maintenance of cell polarity
C	0034727	biological_process	piecemeal microautophagy of the nucleus
C	0035621	biological_process	ER to Golgi ceramide transport
C	0070273	molecular_function	phosphatidylinositol-4-phosphate binding
C	0070300	molecular_function	phosphatidic acid binding
C	0120015	molecular_function	sterol transfer activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 1101

Chain	Residue
A	LEU115
A	ARG347

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 1102

Chain	Residue
A	LYS336
B	VAL208
B	ALA209
B	SER210

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 1103

Chain	Residue
A	LYS247
A	ARG249
A	LYS260

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 1201

Chain	Residue
C	ASN112
C	LYS336

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 1202

Chain	Residue
C	LYS247
C	ARG249
C	LYS260

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 1301

Chain	Residue
B	LYS247
B	ARG249
B	LYS260

Functional Information from PROSITE/UniProt

site_id	PS01013
Number of Residues	11
Details	OSBP Oxysterol-binding protein family signature. EQvSHHPPv.TA

Chain	Residue	Details
A	GLU139-ALA149

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0007744\|PDB:1ZHZ

Chain	Residue	Details
A	GLN96
B	GLN96
C	GLN96

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0007744\|PDB:1ZHT

Chain	Residue	Details
A	ARG100
B	ARG100
C	ARG100

site_id	SWS_FT_FI3
Number of Residues	15
Details	BINDING: BINDING => ECO:0000269\|PubMed:22162133, ECO:0007744\|PDB:3SPW

Chain	Residue	Details
A	LYS109
B	ARG347
C	LYS109
C	HIS143
C	LEU339
C	GLN343
C	ARG347
A	HIS143
A	LEU339
A	GLN343
A	ARG347
B	LYS109
B	HIS143
B	LEU339
B	GLN343

site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:19779198

Chain	Residue	Details
A	GLU373
B	GLU373
C	GLU373

site_id	SWS_FT_FI5
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18407956

Chain	Residue	Details
A	ASN392
B	ASN392
C	ASN392

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)