1ZHT
Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0005546 | molecular_function | phosphatidylinositol-4,5-bisphosphate binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005829 | cellular_component | cytosol |
| A | 0006665 | biological_process | sphingolipid metabolic process |
| A | 0006869 | biological_process | lipid transport |
| A | 0006887 | biological_process | exocytosis |
| A | 0006892 | biological_process | post-Golgi vesicle-mediated transport |
| A | 0006897 | biological_process | endocytosis |
| A | 0008142 | molecular_function | oxysterol binding |
| A | 0008289 | molecular_function | lipid binding |
| A | 0015248 | molecular_function | obsolete sterol transporter activity |
| A | 0015918 | biological_process | sterol transport |
| A | 0016020 | cellular_component | membrane |
| A | 0030011 | biological_process | maintenance of cell polarity |
| A | 0034727 | biological_process | piecemeal microautophagy of the nucleus |
| A | 0035621 | biological_process | ER to Golgi ceramide transport |
| A | 0070273 | molecular_function | phosphatidylinositol-4-phosphate binding |
| A | 0070300 | molecular_function | phosphatidic acid binding |
| A | 0120015 | molecular_function | sterol transfer activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE HCR A 1001 |
| Chain | Residue |
| A | LEU24 |
| A | GLN96 |
| A | TYR97 |
| A | ARG100 |
| A | GLU107 |
| A | ASN165 |
| A | VAL213 |
| A | HOH1002 |
| A | HOH1029 |
Functional Information from PROSITE/UniProt
| site_id | PS01013 |
| Number of Residues | 11 |
| Details | OSBP Oxysterol-binding protein family signature. EQvSHHPPv.TA |
| Chain | Residue | Details |
| A | GLU139-ALA149 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22162133, ECO:0007744|PDB:3SPW |
| Chain | Residue | Details |
| A | LYS109 | |
| A | HIS143 | |
| A | LYS336 | |
| A | GLU340 | |
| A | ARG344 | |
| A | LEU24 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0007744|PDB:1ZHZ |
| Chain | Residue | Details |
| A | GLN96 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0007744|PDB:1ZHT |
| Chain | Residue | Details |
| A | ARG100 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| A | THR370 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956 |
| Chain | Residue | Details |
| A | SER389 |
