1ZAR
Crystal Structure of A.fulgidus Rio2 Kinase Complexed With ADP and Manganese Ions
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030490 | biological_process | maturation of SSU-rRNA |
| A | 0030688 | cellular_component | preribosome, small subunit precursor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0106310 | molecular_function | protein serine kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 402 |
| Chain | Residue |
| A | ASN223 |
| A | ASP235 |
| A | ADP401 |
| A | HOH423 |
| A | HOH489 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ADP A 401 |
| Chain | Residue |
| A | MET179 |
| A | GLU180 |
| A | ILE182 |
| A | GLU186 |
| A | TYR222 |
| A | ASN223 |
| A | ILE234 |
| A | ASP235 |
| A | MN402 |
| A | HOH423 |
| A | HOH477 |
| A | HOH478 |
| A | HOH564 |
| A | GLU103 |
| A | SER104 |
| A | VAL118 |
| A | LYS120 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 403 |
| Chain | Residue |
| A | ASN153 |
| A | ALA157 |
| A | LYS160 |
| A | SER239 |
| A | GLU241 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 404 |
| Chain | Residue |
| A | GLN162 |
| A | GLY163 |
| A | LEU164 |
| A | VAL166 |
| A | LYS168 |
Functional Information from PROSITE/UniProt
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. IVHgDLSQYNVLV |
| Chain | Residue | Details |
| A | ILE214-VAL226 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15943813","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15341724","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15341724","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15943813","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1TQP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ZAO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15341724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1TQP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
