1ZA0

X-ray structure of putative acyl-ACP desaturase DesA2 from Mycobacterium tuberculosis H37Rv

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0016491	molecular_function	oxidoreductase activity
A	0045300	molecular_function	stearoyl-[ACP] desaturase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 888

Chain	Residue
A	GLU107
A	GLU159
A	GLU189
A	HIS192
A	HOH1082

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 980

Chain	Residue
A	HOH989
A	ILE31
A	TRP32
A	LEU109
A	ASP188

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P22337, ECO:0000305|PubMed:15929999

Chain	Residue	Details
A	GLU107
A	GLU159
A	GLU189
A	HIS192

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P22337

Chain	Residue	Details
A	HIS110

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N-acetylalanine => ECO:0007744|PubMed:21969609

Chain	Residue	Details
A	ALA2

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CROSSLNK: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup) => ECO:0000269|PubMed:20066036

Chain	Residue	Details
A	LYS145

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