1Z9D
Crystal structure of a putative uridylate kinase (UMP-kinase) from Streptococcus pyogenes
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| A | 0006225 | biological_process | UDP biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0033862 | molecular_function | UMP kinase activity |
| A | 0044210 | biological_process | 'de novo' CTP biosynthetic process |
| A | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| B | 0006225 | biological_process | UDP biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0033862 | molecular_function | UMP kinase activity |
| B | 0044210 | biological_process | 'de novo' CTP biosynthetic process |
| B | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| C | 0006225 | biological_process | UDP biosynthetic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0033862 | molecular_function | UMP kinase activity |
| C | 0044210 | biological_process | 'de novo' CTP biosynthetic process |
| C | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | ARG101 |
| A | ARG119 |
| A | ARG128 |
| B | ARG122 |
| B | HOH1024 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1002 |
| Chain | Residue |
| B | HOH1014 |
| C | ARG122 |
| B | ARG101 |
| B | ARG119 |
| B | HIS123 |
| B | ARG128 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1003 |
| Chain | Residue |
| A | ARG119 |
| A | ARG122 |
| C | ARG101 |
| C | ARG119 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1004 |
| Chain | Residue |
| A | SER15 |
| A | LYS163 |
| A | ASN164 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1005 |
| Chain | Residue |
| B | SER15 |
| B | LYS163 |
| B | ASN164 |
| B | HOH1040 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1006 |
| Chain | Residue |
| C | SER15 |
| C | LYS163 |
| C | ASN164 |
| C | HOH1034 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1007 |
| Chain | Residue |
| A | LYS13 |
| A | SER15 |
| A | GLY16 |
| A | GLY54 |
| A | GLY55 |
| A | THR143 |
| A | HOH1024 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1008 |
| Chain | Residue |
| B | SER15 |
| B | GLY16 |
| B | GLY54 |
| B | GLY55 |
| B | THR143 |
| B | HOH1015 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1009 |
| Chain | Residue |
| C | LYS13 |
| C | SER15 |
| C | GLY54 |
| C | GLY55 |
| C | THR143 |
| C | HOH1033 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 27 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01220 |
| Chain | Residue | Details |
| A | LYS13 | |
| B | LYS13 | |
| B | GLY55 | |
| B | GLY56 | |
| B | ARG60 | |
| B | ASP75 | |
| B | ILE136 | |
| B | ASN164 | |
| B | TYR170 | |
| B | ASP173 | |
| C | LYS13 | |
| A | GLY55 | |
| C | GLY55 | |
| C | GLY56 | |
| C | ARG60 | |
| C | ASP75 | |
| C | ILE136 | |
| C | ASN164 | |
| C | TYR170 | |
| C | ASP173 | |
| A | GLY56 | |
| A | ARG60 | |
| A | ASP75 | |
| A | ILE136 | |
| A | ASN164 | |
| A | TYR170 | |
| A | ASP173 |
