1Z9D

Crystal structure of a putative uridylate kinase (UMP-kinase) from Streptococcus pyogenes

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006221	biological_process	pyrimidine nucleotide biosynthetic process
A	0006225	biological_process	UDP biosynthetic process
A	0008152	biological_process	metabolic process
A	0009041	molecular_function	UMP/dUMP kinase activity
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0033862	molecular_function	UMP kinase activity
A	0044210	biological_process	'de novo' CTP biosynthetic process
A	0046940	biological_process	nucleoside monophosphate phosphorylation
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006221	biological_process	pyrimidine nucleotide biosynthetic process
B	0006225	biological_process	UDP biosynthetic process
B	0008152	biological_process	metabolic process
B	0009041	molecular_function	UMP/dUMP kinase activity
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0016740	molecular_function	transferase activity
B	0033862	molecular_function	UMP kinase activity
B	0044210	biological_process	'de novo' CTP biosynthetic process
B	0046940	biological_process	nucleoside monophosphate phosphorylation
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006221	biological_process	pyrimidine nucleotide biosynthetic process
C	0006225	biological_process	UDP biosynthetic process
C	0008152	biological_process	metabolic process
C	0009041	molecular_function	UMP/dUMP kinase activity
C	0016301	molecular_function	kinase activity
C	0016310	biological_process	phosphorylation
C	0016740	molecular_function	transferase activity
C	0033862	molecular_function	UMP kinase activity
C	0044210	biological_process	'de novo' CTP biosynthetic process
C	0046940	biological_process	nucleoside monophosphate phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1001

Chain	Residue
A	ARG101
A	ARG119
A	ARG128
B	ARG122
B	HOH1024

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 1002

Chain	Residue
B	HOH1014
C	ARG122
B	ARG101
B	ARG119
B	HIS123
B	ARG128

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1003

Chain	Residue
A	ARG119
A	ARG122
C	ARG101
C	ARG119

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 1004

Chain	Residue
A	SER15
A	LYS163
A	ASN164

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 1005

Chain	Residue
B	SER15
B	LYS163
B	ASN164
B	HOH1040

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 1006

Chain	Residue
C	SER15
C	LYS163
C	ASN164
C	HOH1034

---

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 1007

Chain	Residue
A	LYS13
A	SER15
A	GLY16
A	GLY54
A	GLY55
A	THR143
A	HOH1024

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 1008

Chain	Residue
B	SER15
B	GLY16
B	GLY54
B	GLY55
B	THR143
B	HOH1015

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 1009

Chain	Residue
C	LYS13
C	SER15
C	GLY54
C	GLY55
C	THR143
C	HOH1033

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	27
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01220

Chain	Residue	Details
A	LYS13
B	LYS13
B	GLY55
B	GLY56
B	ARG60
B	ASP75
B	ILE136
B	ASN164
B	TYR170
B	ASP173
C	LYS13
A	GLY55
C	GLY55
C	GLY56
C	ARG60
C	ASP75
C	ILE136
C	ASN164
C	TYR170
C	ASP173
A	GLY56
A	ARG60
A	ASP75
A	ILE136
A	ASN164
A	TYR170
A	ASP173

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