1Z88

Crystal structure of Lys154Arg mutant of mature AphA of S. typhimurium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003993	molecular_function	acid phosphatase activity
A	0016787	molecular_function	hydrolase activity
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding
B	0003993	molecular_function	acid phosphatase activity
B	0016787	molecular_function	hydrolase activity
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0042597	cellular_component	periplasmic space
B	0046872	molecular_function	metal ion binding
C	0003993	molecular_function	acid phosphatase activity
C	0016787	molecular_function	hydrolase activity
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0042597	cellular_component	periplasmic space
C	0046872	molecular_function	metal ion binding
D	0003993	molecular_function	acid phosphatase activity
D	0016787	molecular_function	hydrolase activity
D	0030288	cellular_component	outer membrane-bounded periplasmic space
D	0042597	cellular_component	periplasmic space
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 601

Chain	Residue
A	ASP46
A	ASP48
A	ASP169
A	HOH603
A	HOH604
A	HOH698

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 602

Chain	Residue
B	HOH609
B	HOH689
B	HOH690
B	ASP46
B	ASP48
B	ASP169

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 603

Chain	Residue
D	ASP46
D	ASP48
D	ASP169
D	HOH613
D	HOH713
D	HOH714

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 604

Chain	Residue
C	ASP46
C	ASP48
C	ASP169
C	HOH610
C	HOH611
C	HOH683

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:17570338

Chain	Residue	Details
A	ASP46
B	ASP46
C	ASP46
D	ASP46

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000269|PubMed:17570338

Chain	Residue	Details
A	ASP48
B	ASP48
C	ASP48
D	ASP48

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	BINDING: BINDING => ECO:0000269|PubMed:17570338

Chain	Residue	Details
A	ASP46
B	ASP169
C	ASP46
C	ASP48
C	THR114
C	ARG154
C	ASP169
D	ASP46
D	ASP48
D	THR114
D	ARG154
A	ASP48
D	ASP169
A	THR114
A	ARG154
A	ASP169
B	ASP46
B	ASP48
B	THR114
B	ARG154

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1q91

Chain	Residue	Details
A	ASP48
A	ASP46

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1q91

Chain	Residue	Details
B	ASP48
B	ASP46

---

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1q91

Chain	Residue	Details
C	ASP48
C	ASP46

---

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1q91

Chain	Residue	Details
D	ASP48
D	ASP46

---