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1Z6X

Structure Of Human ADP-Ribosylation Factor 4

Functional Information from GO Data
ChainGOidnamespacecontents
A0000139cellular_componentGolgi membrane
A0003924molecular_functionGTPase activity
A0005085molecular_functionguanyl-nucleotide exchange factor activity
A0005154molecular_functionepidermal growth factor receptor binding
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0005794cellular_componentGolgi apparatus
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006886biological_processintracellular protein transport
A0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
A0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
A0007612biological_processlearning
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0016192biological_processvesicle-mediated transport
A0016477biological_processcell migration
A0032587cellular_componentruffle membrane
A0043066biological_processnegative regulation of apoptotic process
A0043197cellular_componentdendritic spine
A0045176biological_processapical protein localization
A0045197biological_processestablishment or maintenance of epithelial cell apical/basal polarity
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0050807biological_processregulation of synapse organization
A0060271biological_processcilium assembly
A0060996biological_processdendritic spine development
A0061512biological_processprotein localization to cilium
A0070062cellular_componentextracellular exosome
A0098978cellular_componentglutamatergic synapse
A0099175biological_processregulation of postsynapse organization
A0106274molecular_functionNAD+-protein-arginine ADP-ribosyltransferase activity
A1902017biological_processregulation of cilium assembly
A1990583molecular_functionphospholipase D activator activity
A2000377biological_processregulation of reactive oxygen species metabolic process
B0000139cellular_componentGolgi membrane
B0003924molecular_functionGTPase activity
B0005085molecular_functionguanyl-nucleotide exchange factor activity
B0005154molecular_functionepidermal growth factor receptor binding
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005737cellular_componentcytoplasm
B0005794cellular_componentGolgi apparatus
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006886biological_processintracellular protein transport
B0006888biological_processendoplasmic reticulum to Golgi vesicle-mediated transport
B0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
B0007612biological_processlearning
B0015031biological_processprotein transport
B0016020cellular_componentmembrane
B0016192biological_processvesicle-mediated transport
B0016477biological_processcell migration
B0032587cellular_componentruffle membrane
B0043066biological_processnegative regulation of apoptotic process
B0043197cellular_componentdendritic spine
B0045176biological_processapical protein localization
B0045197biological_processestablishment or maintenance of epithelial cell apical/basal polarity
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0050807biological_processregulation of synapse organization
B0060271biological_processcilium assembly
B0060996biological_processdendritic spine development
B0061512biological_processprotein localization to cilium
B0070062cellular_componentextracellular exosome
B0098978cellular_componentglutamatergic synapse
B0099175biological_processregulation of postsynapse organization
B0106274molecular_functionNAD+-protein-arginine ADP-ribosyltransferase activity
B1902017biological_processregulation of cilium assembly
B1990583molecular_functionphospholipase D activator activity
B2000377biological_processregulation of reactive oxygen species metabolic process
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE MG A 200
ChainResidue
ATHR31
AGLU54
AGDP201

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE MG B 202
ChainResidue
BTHR31
BGLU54
BGDP203

site_idAC3
Number of Residues14
DetailsBINDING SITE FOR RESIDUE GDP A 201
ChainResidue
ALYS30
ATHR31
ATHR32
AASN126
ALYS127
AASP129
ALEU130
ACYS159
AALA160
ATHR161
AMG200
AALA27
AALA28
AGLY29

site_idAC4
Number of Residues15
DetailsBINDING SITE FOR RESIDUE GDP B 203
ChainResidue
BASP26
BALA27
BALA28
BGLY29
BLYS30
BTHR31
BTHR32
BASN126
BLYS127
BASP129
BLEU130
BCYS159
BALA160
BTHR161
BMG202

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING:
ChainResidueDetails
ALEU25
AVAL68
ALYS127
BLEU25
BVAL68
BLYS127

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
ALEU148
BLEU148

site_idSWS_FT_FI3
Number of Residues2
DetailsLIPID: N-myristoyl glycine => ECO:0000269|PubMed:25255805
ChainResidueDetails
ALEU3
BLEU3

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
AGLN71

site_idCSA2
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
BGLN71

219140

PDB entries from 2024-05-01

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