1Z6O

Crystal Structure of Trichoplusia ni secreted ferritin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0046872	molecular_function	metal ion binding
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005794	cellular_component	Golgi apparatus
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0008198	molecular_function	ferrous iron binding
B	0008199	molecular_function	ferric iron binding
B	0046872	molecular_function	metal ion binding
C	0005576	cellular_component	extracellular region
C	0005737	cellular_component	cytoplasm
C	0005794	cellular_component	Golgi apparatus
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0008198	molecular_function	ferrous iron binding
C	0008199	molecular_function	ferric iron binding
C	0046872	molecular_function	metal ion binding
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0005794	cellular_component	Golgi apparatus
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0008198	molecular_function	ferrous iron binding
D	0008199	molecular_function	ferric iron binding
D	0046872	molecular_function	metal ion binding
E	0005576	cellular_component	extracellular region
E	0005737	cellular_component	cytoplasm
E	0005794	cellular_component	Golgi apparatus
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0008198	molecular_function	ferrous iron binding
E	0008199	molecular_function	ferric iron binding
E	0046872	molecular_function	metal ion binding
F	0005576	cellular_component	extracellular region
F	0005737	cellular_component	cytoplasm
F	0005794	cellular_component	Golgi apparatus
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0008198	molecular_function	ferrous iron binding
F	0008199	molecular_function	ferric iron binding
F	0046872	molecular_function	metal ion binding
G	0005576	cellular_component	extracellular region
G	0005737	cellular_component	cytoplasm
G	0005794	cellular_component	Golgi apparatus
G	0006826	biological_process	iron ion transport
G	0006879	biological_process	intracellular iron ion homeostasis
G	0008198	molecular_function	ferrous iron binding
G	0008199	molecular_function	ferric iron binding
G	0046872	molecular_function	metal ion binding
H	0005576	cellular_component	extracellular region
H	0005737	cellular_component	cytoplasm
H	0005794	cellular_component	Golgi apparatus
H	0006826	biological_process	iron ion transport
H	0006879	biological_process	intracellular iron ion homeostasis
H	0008198	molecular_function	ferrous iron binding
H	0008199	molecular_function	ferric iron binding
H	0046872	molecular_function	metal ion binding
I	0005576	cellular_component	extracellular region
I	0005737	cellular_component	cytoplasm
I	0005794	cellular_component	Golgi apparatus
I	0006826	biological_process	iron ion transport
I	0006879	biological_process	intracellular iron ion homeostasis
I	0008198	molecular_function	ferrous iron binding
I	0008199	molecular_function	ferric iron binding
I	0046872	molecular_function	metal ion binding
J	0005576	cellular_component	extracellular region
J	0005737	cellular_component	cytoplasm
J	0005794	cellular_component	Golgi apparatus
J	0006826	biological_process	iron ion transport
J	0006879	biological_process	intracellular iron ion homeostasis
J	0008198	molecular_function	ferrous iron binding
J	0008199	molecular_function	ferric iron binding
J	0046872	molecular_function	metal ion binding
K	0005576	cellular_component	extracellular region
K	0005737	cellular_component	cytoplasm
K	0005794	cellular_component	Golgi apparatus
K	0006826	biological_process	iron ion transport
K	0006879	biological_process	intracellular iron ion homeostasis
K	0008198	molecular_function	ferrous iron binding
K	0008199	molecular_function	ferric iron binding
K	0046872	molecular_function	metal ion binding
L	0005576	cellular_component	extracellular region
L	0005737	cellular_component	cytoplasm
L	0005794	cellular_component	Golgi apparatus
L	0006826	biological_process	iron ion transport
L	0006879	biological_process	intracellular iron ion homeostasis
L	0008198	molecular_function	ferrous iron binding
L	0008199	molecular_function	ferric iron binding
L	0046872	molecular_function	metal ion binding
M	0004322	molecular_function	ferroxidase activity
M	0005506	molecular_function	iron ion binding
M	0005576	cellular_component	extracellular region
M	0005737	cellular_component	cytoplasm
M	0005794	cellular_component	Golgi apparatus
M	0006826	biological_process	iron ion transport
M	0006879	biological_process	intracellular iron ion homeostasis
M	0008198	molecular_function	ferrous iron binding
M	0008199	molecular_function	ferric iron binding
M	0016491	molecular_function	oxidoreductase activity
M	0046872	molecular_function	metal ion binding
N	0004322	molecular_function	ferroxidase activity
N	0005506	molecular_function	iron ion binding
N	0005576	cellular_component	extracellular region
N	0005737	cellular_component	cytoplasm
N	0005794	cellular_component	Golgi apparatus
N	0006826	biological_process	iron ion transport
N	0006879	biological_process	intracellular iron ion homeostasis
N	0008198	molecular_function	ferrous iron binding
N	0008199	molecular_function	ferric iron binding
N	0016491	molecular_function	oxidoreductase activity
N	0046872	molecular_function	metal ion binding
O	0004322	molecular_function	ferroxidase activity
O	0005506	molecular_function	iron ion binding
O	0005576	cellular_component	extracellular region
O	0005737	cellular_component	cytoplasm
O	0005794	cellular_component	Golgi apparatus
O	0006826	biological_process	iron ion transport
O	0006879	biological_process	intracellular iron ion homeostasis
O	0008198	molecular_function	ferrous iron binding
O	0008199	molecular_function	ferric iron binding
O	0016491	molecular_function	oxidoreductase activity
O	0046872	molecular_function	metal ion binding
P	0004322	molecular_function	ferroxidase activity
P	0005506	molecular_function	iron ion binding
P	0005576	cellular_component	extracellular region
P	0005737	cellular_component	cytoplasm
P	0005794	cellular_component	Golgi apparatus
P	0006826	biological_process	iron ion transport
P	0006879	biological_process	intracellular iron ion homeostasis
P	0008198	molecular_function	ferrous iron binding
P	0008199	molecular_function	ferric iron binding
P	0016491	molecular_function	oxidoreductase activity
P	0046872	molecular_function	metal ion binding
Q	0004322	molecular_function	ferroxidase activity
Q	0005506	molecular_function	iron ion binding
Q	0005576	cellular_component	extracellular region
Q	0005737	cellular_component	cytoplasm
Q	0005794	cellular_component	Golgi apparatus
Q	0006826	biological_process	iron ion transport
Q	0006879	biological_process	intracellular iron ion homeostasis
Q	0008198	molecular_function	ferrous iron binding
Q	0008199	molecular_function	ferric iron binding
Q	0016491	molecular_function	oxidoreductase activity
Q	0046872	molecular_function	metal ion binding
R	0004322	molecular_function	ferroxidase activity
R	0005506	molecular_function	iron ion binding
R	0005576	cellular_component	extracellular region
R	0005737	cellular_component	cytoplasm
R	0005794	cellular_component	Golgi apparatus
R	0006826	biological_process	iron ion transport
R	0006879	biological_process	intracellular iron ion homeostasis
R	0008198	molecular_function	ferrous iron binding
R	0008199	molecular_function	ferric iron binding
R	0016491	molecular_function	oxidoreductase activity
R	0046872	molecular_function	metal ion binding
S	0004322	molecular_function	ferroxidase activity
S	0005506	molecular_function	iron ion binding
S	0005576	cellular_component	extracellular region
S	0005737	cellular_component	cytoplasm
S	0005794	cellular_component	Golgi apparatus
S	0006826	biological_process	iron ion transport
S	0006879	biological_process	intracellular iron ion homeostasis
S	0008198	molecular_function	ferrous iron binding
S	0008199	molecular_function	ferric iron binding
S	0016491	molecular_function	oxidoreductase activity
S	0046872	molecular_function	metal ion binding
T	0004322	molecular_function	ferroxidase activity
T	0005506	molecular_function	iron ion binding
T	0005576	cellular_component	extracellular region
T	0005737	cellular_component	cytoplasm
T	0005794	cellular_component	Golgi apparatus
T	0006826	biological_process	iron ion transport
T	0006879	biological_process	intracellular iron ion homeostasis
T	0008198	molecular_function	ferrous iron binding
T	0008199	molecular_function	ferric iron binding
T	0016491	molecular_function	oxidoreductase activity
T	0046872	molecular_function	metal ion binding
U	0004322	molecular_function	ferroxidase activity
U	0005506	molecular_function	iron ion binding
U	0005576	cellular_component	extracellular region
U	0005737	cellular_component	cytoplasm
U	0005794	cellular_component	Golgi apparatus
U	0006826	biological_process	iron ion transport
U	0006879	biological_process	intracellular iron ion homeostasis
U	0008198	molecular_function	ferrous iron binding
U	0008199	molecular_function	ferric iron binding
U	0016491	molecular_function	oxidoreductase activity
U	0046872	molecular_function	metal ion binding
V	0004322	molecular_function	ferroxidase activity
V	0005506	molecular_function	iron ion binding
V	0005576	cellular_component	extracellular region
V	0005737	cellular_component	cytoplasm
V	0005794	cellular_component	Golgi apparatus
V	0006826	biological_process	iron ion transport
V	0006879	biological_process	intracellular iron ion homeostasis
V	0008198	molecular_function	ferrous iron binding
V	0008199	molecular_function	ferric iron binding
V	0016491	molecular_function	oxidoreductase activity
V	0046872	molecular_function	metal ion binding
W	0004322	molecular_function	ferroxidase activity
W	0005506	molecular_function	iron ion binding
W	0005576	cellular_component	extracellular region
W	0005737	cellular_component	cytoplasm
W	0005794	cellular_component	Golgi apparatus
W	0006826	biological_process	iron ion transport
W	0006879	biological_process	intracellular iron ion homeostasis
W	0008198	molecular_function	ferrous iron binding
W	0008199	molecular_function	ferric iron binding
W	0016491	molecular_function	oxidoreductase activity
W	0046872	molecular_function	metal ion binding
X	0004322	molecular_function	ferroxidase activity
X	0005506	molecular_function	iron ion binding
X	0005576	cellular_component	extracellular region
X	0005737	cellular_component	cytoplasm
X	0005794	cellular_component	Golgi apparatus
X	0006826	biological_process	iron ion transport
X	0006879	biological_process	intracellular iron ion homeostasis
X	0008198	molecular_function	ferrous iron binding
X	0008199	molecular_function	ferric iron binding
X	0016491	molecular_function	oxidoreductase activity
X	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE A 301

Chain	Residue
A	GLU165
A	HOH5443
E	GLU165
E	HOH370
L	GLU165
L	HOH217

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 5302

Chain	Residue
E	GLU164
L	GLN161
L	GLU164
A	GLN161
A	GLU164
E	GLN161

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 5303

Chain	Residue
A	GLU164
A	HOH5324
E	GLU164
E	HOH247
L	GLU164
L	HOH213
L	HOH254

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE B 301

Chain	Residue
B	GLU165
B	HOH6457
D	GLU165
D	HOH552
K	GLU165
K	HOH1296

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 6302

Chain	Residue
B	GLN161
B	GLU164
D	GLN161
D	GLU164
K	GLN161
K	GLU164

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA B 6303

Chain	Residue
B	GLU164
B	HOH6326
D	GLU164
D	HOH376
D	HOH1201
K	GLU164
K	HOH3797

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE C 301

Chain	Residue
C	GLU165
C	HOH2785
H	GLU165
H	HOH3154
I	GLU165
I	HOH924

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 7302

Chain	Residue
C	GLN161
C	GLU164
H	GLN161
H	GLU164
I	GLN161
I	GLU164

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA C 7303

Chain	Residue
C	GLU164
C	HOH829
H	GLU164
H	HOH748
H	HOH2690
I	GLU164
I	HOH3059

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE F 301

Chain	Residue
F	GLU165
F	HOH2413
G	GLU165
G	HOH3523
J	GLU165
J	HOH2039

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA F 8302

Chain	Residue
F	GLN161
F	GLU164
G	GLN161
G	GLU164
J	GLN161
J	GLU164

---

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA F 8303

Chain	Residue
F	GLU164
F	HOH1863
F	HOH1944
G	GLU164
G	HOH2318
J	GLU164
J	HOH3428

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE M 300

Chain	Residue
M	GLU32
M	GLU67
M	HIS70
M	HOH330
M	HOH333

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE N 300

Chain	Residue
N	GLU32
N	GLU67
N	HIS70
N	HOH332
N	HOH334

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE O 300

Chain	Residue
O	GLU32
O	GLU67
O	HIS70
O	HOH351
O	HOH354

---

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE P 300

Chain	Residue
P	GLU32
P	GLU67
P	HIS70
P	HOH335
P	HOH338

---

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE Q 300

Chain	Residue
Q	HOH1541
Q	HOH1547
Q	GLU32
Q	GLU67
Q	HIS70

---

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE R 300

Chain	Residue
R	GLU32
R	GLU67
R	HIS70
R	HOH1913
R	HOH1919

---

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE S 300

Chain	Residue
S	GLU32
S	GLU67
S	HIS70
S	HOH2287
S	HOH2293

---

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE T 300

Chain	Residue
T	GLU32
T	GLU67
T	HIS70
T	HOH2659
T	HOH2665

---

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE U 300

Chain	Residue
U	GLU32
U	GLU67
U	HIS70
U	HOH3028
U	HOH3034

---

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE V 300

Chain	Residue
V	GLU32
V	GLU67
V	HIS70
V	HOH3397
V	HOH3403

---

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE W 300

Chain	Residue
W	GLU32
W	GLU67
W	HIS70
W	HOH3766
W	HOH3772

---

site_id	CC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE X 300

Chain	Residue
X	GLU32
X	GLU67
X	HIS70
X	HOH354
X	HOH357

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3768
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15896348","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Z6O","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15896348","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---