1Z5X

hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0003677	molecular_function	DNA binding
E	0004879	molecular_function	nuclear receptor activity
E	0005634	cellular_component	nucleus
E	0006355	biological_process	regulation of DNA-templated transcription
E	0035076	biological_process	ecdysone receptor signaling pathway
E	0035100	molecular_function	ecdysone binding
U	0003677	molecular_function	DNA binding
U	0003707	molecular_function	nuclear steroid receptor activity
U	0005634	cellular_component	nucleus
U	0006355	biological_process	regulation of DNA-templated transcription
U	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 U 1

Chain	Residue
E	GLU336
E	ARG337
E	ARG384
U	ARG383
U	GLU387
U	ARG456
U	ALA459

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 U 2

Chain	Residue
U	PRO444
U	ASP445
U	GLN446
U	HIS323
U	TYR443

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 U 3

Chain	Residue
E	TYR193
E	PHE194
E	GLU197
E	ARG244
U	HIS470

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 E 4

Chain	Residue
E	ARG223
E	GLU294
E	SER295

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site_id	AC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE P1A E 5

Chain	Residue
E	GLU199
E	PRO201
E	ILE230
E	THR231
E	THR234
E	MET268
E	ARG271
E	MET272
E	ARG275
E	PHE285
E	ALA286
E	TYR296
E	LEU308
E	ASN390
E	TRP412

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