1Z5B
Topoisomerase VI-B, ADP AlF4- bound dimer form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006265 | biological_process | DNA topological change |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 2001 |
| Chain | Residue |
| A | ASN42 |
| A | ADP1001 |
| A | ALF3001 |
| A | HOH4038 |
| A | HOH4136 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ALF A 3001 |
| Chain | Residue |
| A | GLY109 |
| A | LEU110 |
| A | GLY111 |
| A | LYS427 |
| A | ADP1001 |
| A | MG2001 |
| A | HOH4002 |
| A | HOH4038 |
| A | HOH4136 |
| A | HOH4137 |
| A | GLU38 |
| A | GLY106 |
| A | MET107 |
| A | TYR108 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 2002 |
| Chain | Residue |
| B | ASN42 |
| B | ADP1002 |
| B | ALF3002 |
| B | HOH3008 |
| B | HOH3165 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ALF B 3002 |
| Chain | Residue |
| B | GLU38 |
| B | GLY106 |
| B | MET107 |
| B | TYR108 |
| B | GLY109 |
| B | LEU110 |
| B | GLY111 |
| B | LYS427 |
| B | ADP1002 |
| B | MG2002 |
| B | HOH3003 |
| B | HOH3008 |
| B | HOH3089 |
| B | HOH3165 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 4001 |
| Chain | Residue |
| A | GLY266 |
| A | ASP267 |
| A | THR268 |
| A | THR269 |
| A | ARG307 |
| A | HOH4005 |
| B | ARG307 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 2003 |
| Chain | Residue |
| B | ARG102 |
| B | THR418 |
| B | HOH3030 |
| B | HOH3069 |
| site_id | AC7 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE ADP A 1001 |
| Chain | Residue |
| A | ASN42 |
| A | ALA46 |
| A | ASP76 |
| A | GLY80 |
| A | ILE81 |
| A | ALA89 |
| A | TYR95 |
| A | SER96 |
| A | SER97 |
| A | LYS98 |
| A | GLY106 |
| A | MET107 |
| A | TYR108 |
| A | GLY109 |
| A | LEU110 |
| A | GLY111 |
| A | VAL112 |
| A | LYS113 |
| A | MG2001 |
| A | ALF3001 |
| A | HOH4004 |
| A | HOH4009 |
| A | HOH4011 |
| A | HOH4012 |
| A | HOH4136 |
| B | PHE7 |
| site_id | AC8 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE ADP B 1002 |
| Chain | Residue |
| B | HOH3016 |
| B | HOH3165 |
| A | PHE7 |
| B | ASN42 |
| B | ALA46 |
| B | ASP76 |
| B | GLY80 |
| B | ILE81 |
| B | ALA89 |
| B | TYR95 |
| B | SER96 |
| B | SER97 |
| B | LYS98 |
| B | MET107 |
| B | TYR108 |
| B | GLY109 |
| B | LEU110 |
| B | GLY111 |
| B | VAL112 |
| B | LYS113 |
| B | THR170 |
| B | MG2002 |
| B | ALF3002 |
| B | HOH3007 |
| B | HOH3008 |
| B | HOH3010 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12505993","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15939019","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1MX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z59","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z5A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z5B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z5C","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12505993","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15939019","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1MX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z5A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z5B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z5C","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12505993","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1MX0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
