1Z59

Topoisomerase VI-B, ADP-bound monomer form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0006265	biological_process	DNA topological change

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 1001

Chain	Residue
A	ASN42
A	ADP2001
A	HOH2015
A	HOH2059
A	HOH2084

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site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ADP A 2001

Chain	Residue
A	ILE81
A	ALA89
A	LEU110
A	VAL112
A	LYS113
A	THR170
A	MG1001
A	HOH2006
A	HOH2013
A	HOH2015
A	HOH2059
A	HOH2069
A	HOH2112
A	ASN42
A	ALA46
A	ASP76
A	GLY80

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:12505993, ECO:0000269|PubMed:15939019, ECO:0007744|PDB:1MX0, ECO:0007744|PDB:1Z59, ECO:0007744|PDB:1Z5A, ECO:0007744|PDB:1Z5B, ECO:0007744|PDB:1Z5C

Chain	Residue	Details
A	ASN42
A	ASP76
A	MSE107

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:12505993, ECO:0000269|PubMed:15939019, ECO:0007744|PDB:1MX0, ECO:0007744|PDB:1Z5A, ECO:0007744|PDB:1Z5B, ECO:0007744|PDB:1Z5C

Chain	Residue	Details
A	SER96

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:12505993, ECO:0007744|PDB:1MX0

Chain	Residue	Details
A	LYS427

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