1Z59

Topoisomerase VI-B, ADP-bound monomer form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0006265	biological_process	DNA topological change

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 1001

Chain	Residue
A	ASN42
A	ADP2001
A	HOH2015
A	HOH2059
A	HOH2084

---

site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ADP A 2001

Chain	Residue
A	ILE81
A	ALA89
A	LEU110
A	VAL112
A	LYS113
A	THR170
A	MG1001
A	HOH2006
A	HOH2013
A	HOH2015
A	HOH2059
A	HOH2069
A	HOH2112
A	ASN42
A	ALA46
A	ASP76
A	GLY80

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12505993","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15939019","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1MX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z59","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z5A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z5B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z5C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12505993","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15939019","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1MX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z5A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z5B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z5C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12505993","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1MX0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---