Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004402 | molecular_function | histone acetyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE ACO A 401 |
| Chain | Residue |
| A | HIS502 |
| A | PHE578 |
| A | CYS579 |
| A | ALA580 |
| A | VAL581 |
| A | GLN586 |
| A | VAL587 |
| A | LYS588 |
| A | GLY589 |
| A | TYR590 |
| A | GLY591 |
| A | ALA512 |
| A | THR592 |
| A | THR612 |
| A | TYR613 |
| A | ASP615 |
| A | TYR617 |
| A | GLY620 |
| A | TYR621 |
| A | LYS624 |
| A | HOH1002 |
| A | HOH1008 |
| A | ASN513 |
| A | HOH1013 |
| A | HOH1024 |
| A | HOH1033 |
| A | HOH1036 |
| A | HOH1044 |
| A | ARG515 |
| A | TRP519 |
| A | GLN530 |
| A | LEU531 |
| A | ILE576 |
| A | VAL577 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 153 |
| Details | Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Region: {"description":"Loop 3","evidences":[{"source":"PubMed","id":"29211711","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"27796307","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31527837","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29211711","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5TRL","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"23142079","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ygh |
| Chain | Residue | Details |
| A | GLU575 | |
| site_id | CSA2 |
| Number of Residues | 9 |
| Details | Annotated By Reference To The Literature 1ygh |
| Chain | Residue | Details |
| A | ILE642 | |
| A | LEU611 | |
| A | TYR645 | |
| A | GLU575 | |
| A | CYS579 | |
| A | ILE576 | |
| A | VAL577 | |
| A | PHE568 | |
| A | PHE573 | |
| site_id | MCSA1 |
| Number of Residues | 9 |
| Details | M-CSA 524 |
| Chain | Residue | Details |
| A | PHE568 | electrostatic stabiliser |
| A | PHE573 | electrostatic stabiliser |
| A | GLU575 | proton acceptor |
| A | ILE576 | electrostatic stabiliser |
| A | VAL577 | electrostatic stabiliser |
| A | CYS579 | electrostatic stabiliser |
| A | LEU611 | electrostatic stabiliser |
| A | ILE642 | electrostatic stabiliser |
| A | TYR645 | electrostatic stabiliser |
