1Z3P

X-Ray crystal structure of a mutant Ribonuclease S (M13Nva)

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0003676	molecular_function	nucleic acid binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 125

Chain	Residue
E	HIS119
E	PHE120
E	HOH241
S	HIS12

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E 126

Chain	Residue
E	SER50
E	LEU51
E	LYS61
E	HOH207
S	SER15

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Functional Information from PROSITE/UniProt

site_id	PS00127
Number of Residues	7
Details	RNASE_PANCREATIC Pancreatic ribonuclease family signature. CKpvNTF

Chain	Residue	Details
E	CYS40-PHE46

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor

Chain	Residue	Details
E	HIS119

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING:

Chain	Residue	Details
E	LYS41
E	LYS66
E	ARG85

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; partial => ECO:0000269|PubMed:19358553

Chain	Residue	Details
E	ASN34
S	LYS7

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CARBOHYD: N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761

Chain	Residue	Details
E	LYS37
E	LYS41

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	4
Details	M-CSA 164

Chain	Residue	Details
E	LYS41	electrostatic stabiliser, hydrogen bond donor
E	HIS119	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
E	PHE120	electrostatic stabiliser, hydrogen bond donor
E	ASP121	electrostatic stabiliser, hydrogen bond acceptor

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