1Z3A
Crystal structure of tRNA adenosine deaminase TadA from Escherichia coli
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0006382 | biological_process | adenosine to inosine editing |
| A | 0008033 | biological_process | tRNA processing |
| A | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052717 | molecular_function | tRNA-specific adenosine-34 deaminase activity |
| B | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0006382 | biological_process | adenosine to inosine editing |
| B | 0008033 | biological_process | tRNA processing |
| B | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052717 | molecular_function | tRNA-specific adenosine-34 deaminase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 301 |
| Chain | Residue |
| A | HIS68 |
| A | CYS98 |
| A | CYS101 |
| A | HOH416 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 302 |
| Chain | Residue |
| B | HIS68 |
| B | CYS98 |
| B | CYS101 |
| B | HOH413 |
Functional Information from PROSITE/UniProt
| site_id | PS00903 |
| Number of Residues | 38 |
| Details | CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAEimALrqgglvmqnyrlidatlyvtle...........PCvm......CagaM |
| Chain | Residue | Details |
| A | HIS68-MET105 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 222 |
| Details | Domain: {"description":"CMP/dCMP-type deaminase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01083","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"16700551","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00972","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16700551","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
