1Z29
Crystal Structures of SULT1A2 and SULT1A1*3: Implications in the bioactivation of N-hydroxy-2-acetylamino fluorine (OH-AAF)
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004062 | molecular_function | aryl sulfotransferase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006068 | biological_process | ethanol catabolic process |
A | 0006584 | biological_process | catecholamine metabolic process |
A | 0006805 | biological_process | xenobiotic metabolic process |
A | 0008146 | molecular_function | sulfotransferase activity |
A | 0008202 | biological_process | steroid metabolic process |
A | 0009309 | biological_process | amine biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0018958 | biological_process | phenol-containing compound metabolic process |
A | 0047894 | molecular_function | flavonol 3-sulfotransferase activity |
A | 0050427 | biological_process | 3'-phosphoadenosine 5'-phosphosulfate metabolic process |
A | 0051923 | biological_process | sulfation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CA A 1010 |
Chain | Residue |
A | LYS106 |
A | TYR240 |
A | ACY721 |
A | HOH2057 |
site_id | AC2 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE A3P A 2001 |
Chain | Residue |
A | TRP53 |
A | ARG130 |
A | SER138 |
A | TYR193 |
A | THR227 |
A | SER228 |
A | PHE229 |
A | MET232 |
A | PHE255 |
A | MET256 |
A | ARG257 |
A | LYS258 |
A | GLY259 |
A | HOH2005 |
A | HOH2012 |
A | HOH2013 |
A | HOH2025 |
A | LYS48 |
A | SER49 |
A | GLY50 |
A | THR51 |
A | THR52 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE ACY A 721 |
Chain | Residue |
A | PHE81 |
A | LYS106 |
A | HIS108 |
A | TYR149 |
A | CA1010 |
A | HOH2011 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton acceptor => ECO:0000250 |
Chain | Residue | Details |
A | HIS108 |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | BINDING: |
Chain | Residue | Details |
A | LYS48 | |
A | ARG130 | |
A | SER138 | |
A | TYR193 | |
A | THR227 | |
A | PHE255 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | LYS106 |