1Z29
Crystal Structures of SULT1A2 and SULT1A1*3: Implications in the bioactivation of N-hydroxy-2-acetylamino fluorine (OH-AAF)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004062 | molecular_function | aryl sulfotransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006068 | biological_process | ethanol catabolic process |
| A | 0006584 | biological_process | catecholamine metabolic process |
| A | 0006805 | biological_process | xenobiotic metabolic process |
| A | 0008146 | molecular_function | sulfotransferase activity |
| A | 0008202 | biological_process | steroid metabolic process |
| A | 0009309 | biological_process | amine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0018958 | biological_process | phenol-containing compound metabolic process |
| A | 0047894 | molecular_function | flavonol 3-sulfotransferase activity |
| A | 0050427 | biological_process | 3'-phosphoadenosine 5'-phosphosulfate metabolic process |
| A | 0051923 | biological_process | sulfation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 1010 |
| Chain | Residue |
| A | LYS106 |
| A | TYR240 |
| A | ACY721 |
| A | HOH2057 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE A3P A 2001 |
| Chain | Residue |
| A | TRP53 |
| A | ARG130 |
| A | SER138 |
| A | TYR193 |
| A | THR227 |
| A | SER228 |
| A | PHE229 |
| A | MET232 |
| A | PHE255 |
| A | MET256 |
| A | ARG257 |
| A | LYS258 |
| A | GLY259 |
| A | HOH2005 |
| A | HOH2012 |
| A | HOH2013 |
| A | HOH2025 |
| A | LYS48 |
| A | SER49 |
| A | GLY50 |
| A | THR51 |
| A | THR52 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACY A 721 |
| Chain | Residue |
| A | PHE81 |
| A | LYS106 |
| A | HIS108 |
| A | TYR149 |
| A | CA1010 |
| A | HOH2011 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS108 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LYS48 | |
| A | ARG130 | |
| A | SER138 | |
| A | TYR193 | |
| A | THR227 | |
| A | PHE255 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | LYS106 |
