1Z0Z

Crystal structure of a NAD kinase from Archaeoglobus fulgidus in complex with NAD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003951	molecular_function	NAD+ kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006741	biological_process	NADP+ biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
A	0019674	biological_process	NAD+ metabolic process
A	0046872	molecular_function	metal ion binding
A	0051287	molecular_function	NAD binding
B	0000166	molecular_function	nucleotide binding
B	0003951	molecular_function	NAD+ kinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006741	biological_process	NADP+ biosynthetic process
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
B	0019674	biological_process	NAD+ metabolic process
B	0046872	molecular_function	metal ion binding
B	0051287	molecular_function	NAD binding
C	0000166	molecular_function	nucleotide binding
C	0003951	molecular_function	NAD+ kinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006741	biological_process	NADP+ biosynthetic process
C	0016301	molecular_function	kinase activity
C	0016740	molecular_function	transferase activity
C	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
C	0019674	biological_process	NAD+ metabolic process
C	0046872	molecular_function	metal ion binding
C	0051287	molecular_function	NAD binding
D	0000166	molecular_function	nucleotide binding
D	0003951	molecular_function	NAD+ kinase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006741	biological_process	NADP+ biosynthetic process
D	0016301	molecular_function	kinase activity
D	0016740	molecular_function	transferase activity
D	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
D	0019674	biological_process	NAD+ metabolic process
D	0046872	molecular_function	metal ion binding
D	0051287	molecular_function	NAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE NAD A 3075

Chain	Residue
A	LEU75
D	ALA125
D	LYS126
D	MET127
D	ARG143
D	ASP145
D	ALA180
D	PHE182
A	ASN115
A	GLU116
A	ILE153
A	THR156
A	TYR158
A	SER161
A	ASP209
A	GLY210

---

site_id	AC2
Number of Residues	20
Details	BINDING SITE FOR RESIDUE NAD B 3076

Chain	Residue
B	ASP49
B	LEU53
B	ARG54
B	ASN115
B	GLU116
B	ILE153
B	THR156
B	GLY157
B	TYR158
B	SER161
B	ASP209
B	GLY210
B	GLN211
C	ALA125
C	LYS126
C	MET127
C	ARG143
C	ASP145
C	ALA180
C	PHE182

---

site_id	AC3
Number of Residues	20
Details	BINDING SITE FOR RESIDUE NAD C 3077

Chain	Residue
B	ALA125
B	LYS126
B	MET127
B	ARG143
B	ASP145
B	ALA180
B	PHE182
C	ASP49
C	ARG54
C	ARG72
C	LEU75
C	ASN115
C	GLU116
C	ILE153
C	THR156
C	TYR158
C	SER161
C	ASP209
C	GLY210
C	GLN211

---

site_id	AC4
Number of Residues	19
Details	BINDING SITE FOR RESIDUE NAD D 3078

Chain	Residue
A	ALA125
A	LYS126
A	MET127
A	ARG143
A	ASP145
A	ALA180
A	PHE182
A	HOH3076
D	ASP49
D	LEU75
D	ASN115
D	GLU116
D	ILE153
D	THR156
D	TYR158
D	SER161
D	ASP209
D	GLY210
D	GLN211

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00361","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00361","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16242716","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16242716","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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