1Z0D

GDP-Bound Rab5c GTPase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PO4 A 600

Chain	Residue
A	SER30
A	HOH706
A	HOH760
C	ASN172
A	LYS34
A	ALA78
A	GLY79
A	LEU80
A	GLU81
A	HOH702
A	HOH703
A	HOH704

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 601

Chain	Residue
A	SER35
A	GDP700
A	HOH706
A	HOH709
A	HOH718
A	HOH724

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 800

Chain	Residue
C	SER35
C	GDP900
C	HOH907
C	HOH913
C	HOH916
C	HOH923

---

site_id	AC4
Number of Residues	25
Details	BINDING SITE FOR RESIDUE GDP A 700

Chain	Residue
A	ALA31
A	VAL32
A	GLY33
A	LYS34
A	SER35
A	SER36
A	PHE46
A	HIS47
A	GLU48
A	GLN50
A	ASN134
A	LYS135
A	ASP137
A	LEU138
A	SER164
A	ALA165
A	LYS166
A	MG601
A	HOH706
A	HOH708
A	HOH716
A	HOH718
A	HOH736
A	HOH752
C	THR167

---

site_id	AC5
Number of Residues	22
Details	BINDING SITE FOR RESIDUE GDP C 900

Chain	Residue
C	ALA31
C	VAL32
C	GLY33
C	LYS34
C	SER35
C	SER36
C	PHE46
C	GLU48
C	ASN134
C	LYS135
C	ASP137
C	LEU138
C	SER164
C	ALA165
C	LYS166
C	MG800
C	HOH907
C	HOH916
C	HOH923
C	HOH933
C	HOH945
C	HOH984

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P20339

Chain	Residue	Details
A	GLY28
A	HIS47
A	ASP76
A	ASN134
A	SER164
C	GLY28
C	HIS47
C	ASP76
C	ASN134
C	SER164

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P51148

Chain	Residue	Details
A	SER85
C	SER85

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