1YZU

GppNHp-Bound Rab21 GTPase at 2.50 A Resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0032482	biological_process	Rab protein signal transduction
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding
B	0032482	biological_process	Rab protein signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 300

Chain	Residue
A	THR33
A	THR51
A	GNP301
A	HOH305
A	HOH320

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 400

Chain	Residue
B	HOH407
B	THR33
B	THR51
B	GNP401
B	HOH404

---

site_id	AC3
Number of Residues	28
Details	BINDING SITE FOR RESIDUE GNP A 301

Chain	Residue
A	GLY28
A	CYS29
A	VAL30
A	GLY31
A	LYS32
A	THR33
A	SER34
A	PHE44
A	ASN45
A	ASP46
A	HIS48
A	THR50
A	THR51
A	ASN132
A	LYS133
A	ASP135
A	LEU136
A	SER162
A	ALA163
A	LYS164
A	MG300
A	HOH304
A	HOH305
A	HOH320
A	HOH334
A	HOH362
A	HOH372
A	HOH383

---

site_id	AC4
Number of Residues	26
Details	BINDING SITE FOR RESIDUE GNP B 401

Chain	Residue
B	GLY28
B	CYS29
B	GLY31
B	LYS32
B	THR33
B	SER34
B	PHE44
B	ASN45
B	ASP46
B	HIS48
B	THR50
B	THR51
B	ASN132
B	LYS133
B	ASP135
B	LEU136
B	SER162
B	ALA163
B	LYS164
B	MG400
B	HOH404
B	HOH407
B	HOH413
B	HOH423
B	HOH427
B	HOH434

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	26
Details	Motif: {"description":"Switch 1","evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z08","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z0I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	Motif: {"description":"Switch 2","evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z08","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z0I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	22
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z08","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z08","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z0I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z08","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1Z0I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1Z08","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1YZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YZU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	GLN78

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
B	GLN78

---