Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004603 | molecular_function | phenylethanolamine N-methyltransferase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005829 | cellular_component | cytosol |
A | 0008168 | molecular_function | methyltransferase activity |
A | 0032259 | biological_process | methylation |
A | 0042418 | biological_process | epinephrine biosynthetic process |
A | 0042423 | biological_process | catecholamine biosynthetic process |
B | 0004603 | molecular_function | phenylethanolamine N-methyltransferase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005829 | cellular_component | cytosol |
B | 0008168 | molecular_function | methyltransferase activity |
B | 0032259 | biological_process | methylation |
B | 0042418 | biological_process | epinephrine biosynthetic process |
B | 0042423 | biological_process | catecholamine biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE SKA A 3001 |
Chain | Residue |
A | TYR35 |
A | HOH1040 |
A | ASN39 |
A | TYR40 |
A | VAL53 |
A | LYS57 |
A | PHE182 |
A | GLU219 |
A | MET258 |
A | ASP267 |
site_id | AC2 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE SKA B 3002 |
Chain | Residue |
B | TYR35 |
B | ASN39 |
B | TYR40 |
B | VAL53 |
B | LYS57 |
B | PHE182 |
B | GLU219 |
B | MET258 |
B | ASP267 |
B | VAL269 |
B | VAL272 |
B | HOH1068 |
site_id | AC3 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE SAH B 2001 |
Chain | Residue |
B | TYR27 |
B | TYR35 |
B | TYR40 |
B | GLY79 |
B | SER80 |
B | GLY81 |
B | THR83 |
B | TYR85 |
B | ASP101 |
B | PHE102 |
B | LEU103 |
B | ASN106 |
B | ILE157 |
B | ASP158 |
B | VAL159 |
B | ALA181 |
B | PHE182 |
B | CYS183 |
B | VAL187 |
B | HOH1080 |
site_id | AC4 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE SAH A 2002 |
Chain | Residue |
A | TYR35 |
A | TYR40 |
A | GLY79 |
A | SER80 |
A | GLY81 |
A | THR83 |
A | TYR85 |
A | ASP101 |
A | PHE102 |
A | LEU103 |
A | ASN106 |
A | ASP158 |
A | VAL159 |
A | ALA181 |
A | PHE182 |
A | CYS183 |
A | VAL187 |
A | HOH1039 |
A | HOH1182 |
Functional Information from PROSITE/UniProt
site_id | PS01100 |
Number of Residues | 17 |
Details | NNMT_PNMT_TEMT NNMT/PNMT/TEMT family of methyltransferases signature. LIDIGSGPTVYQLLSAC |
Chain | Residue | Details |
A | LEU75-CYS91 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | TYR35 | |
B | ASP101 | |
B | ASN106 | |
B | ALA181 | |
A | TYR40 | |
A | TYR85 | |
A | ASP101 | |
A | ASN106 | |
A | ALA181 | |
B | TYR35 | |
B | TYR40 | |
B | TYR85 | |
Chain | Residue | Details |
A | GLY79 | |
A | ASP158 | |
B | GLY79 | |
B | ASP158 | |
Chain | Residue | Details |
A | GLU219 | |
A | ASP267 | |
B | GLU219 | |
B | ASP267 | |
Chain | Residue | Details |
A | SER7 | |
B | SER7 | |