1YXM
Crystal structure of peroxisomal trans 2-enoyl CoA reductase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005102 | molecular_function | signaling receptor binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005777 | cellular_component | peroxisome |
| A | 0005778 | cellular_component | peroxisomal membrane |
| A | 0005829 | cellular_component | cytosol |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0008670 | molecular_function | 2,4-dienoyl-CoA reductase (NADPH) activity |
| A | 0019166 | molecular_function | trans-2-enoyl-CoA reductase (NADPH) activity |
| A | 0033306 | biological_process | phytol metabolic process |
| B | 0005102 | molecular_function | signaling receptor binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005777 | cellular_component | peroxisome |
| B | 0005778 | cellular_component | peroxisomal membrane |
| B | 0005829 | cellular_component | cytosol |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0008670 | molecular_function | 2,4-dienoyl-CoA reductase (NADPH) activity |
| B | 0019166 | molecular_function | trans-2-enoyl-CoA reductase (NADPH) activity |
| B | 0033306 | biological_process | phytol metabolic process |
| C | 0005102 | molecular_function | signaling receptor binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005777 | cellular_component | peroxisome |
| C | 0005778 | cellular_component | peroxisomal membrane |
| C | 0005829 | cellular_component | cytosol |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0008670 | molecular_function | 2,4-dienoyl-CoA reductase (NADPH) activity |
| C | 0019166 | molecular_function | trans-2-enoyl-CoA reductase (NADPH) activity |
| C | 0033306 | biological_process | phytol metabolic process |
| D | 0005102 | molecular_function | signaling receptor binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005777 | cellular_component | peroxisome |
| D | 0005778 | cellular_component | peroxisomal membrane |
| D | 0005829 | cellular_component | cytosol |
| D | 0006633 | biological_process | fatty acid biosynthetic process |
| D | 0008670 | molecular_function | 2,4-dienoyl-CoA reductase (NADPH) activity |
| D | 0019166 | molecular_function | trans-2-enoyl-CoA reductase (NADPH) activity |
| D | 0033306 | biological_process | phytol metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 304 |
| Chain | Residue |
| A | GLN17 |
| A | LYS70 |
| A | GLN71 |
| A | ALA72 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1001 |
| Chain | Residue |
| D | HOH2056 |
| D | HOH2086 |
| D | HOH2088 |
| D | THR28 |
| D | GLY29 |
| D | ILE30 |
| D | GLY31 |
| D | ASN107 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 2001 |
| Chain | Residue |
| D | GLY29 |
| D | SER206 |
| D | GLN207 |
| D | THR208 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 B 3001 |
| Chain | Residue |
| B | SER49 |
| B | ARG50 |
| B | LYS51 |
| B | ADE4002 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 4001 |
| Chain | Residue |
| B | GLN17 |
| B | LYS70 |
| B | GLN71 |
| B | ALA72 |
| B | SER219 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ADE B 4002 |
| Chain | Residue |
| B | SER49 |
| B | ARG50 |
| B | CYS79 |
| B | ASN80 |
| B | ILE81 |
| B | GLY109 |
| B | THR130 |
| B | PO43001 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Motif: {"description":"Microbody targeting signal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 96 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q99MZ7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
