1YXM

Crystal structure of peroxisomal trans 2-enoyl CoA reductase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005102	molecular_function	signaling receptor binding
A	0005739	cellular_component	mitochondrion
A	0005777	cellular_component	peroxisome
A	0005778	cellular_component	peroxisomal membrane
A	0005829	cellular_component	cytosol
A	0006633	biological_process	fatty acid biosynthetic process
A	0008670	molecular_function	2,4-dienoyl-CoA reductase (NADPH) activity
A	0016491	molecular_function	oxidoreductase activity
A	0019166	molecular_function	trans-2-enoyl-CoA reductase (NADPH) activity
A	0033306	biological_process	phytol metabolic process
B	0005102	molecular_function	signaling receptor binding
B	0005739	cellular_component	mitochondrion
B	0005777	cellular_component	peroxisome
B	0005778	cellular_component	peroxisomal membrane
B	0005829	cellular_component	cytosol
B	0006633	biological_process	fatty acid biosynthetic process
B	0008670	molecular_function	2,4-dienoyl-CoA reductase (NADPH) activity
B	0016491	molecular_function	oxidoreductase activity
B	0019166	molecular_function	trans-2-enoyl-CoA reductase (NADPH) activity
B	0033306	biological_process	phytol metabolic process
C	0005102	molecular_function	signaling receptor binding
C	0005739	cellular_component	mitochondrion
C	0005777	cellular_component	peroxisome
C	0005778	cellular_component	peroxisomal membrane
C	0005829	cellular_component	cytosol
C	0006633	biological_process	fatty acid biosynthetic process
C	0008670	molecular_function	2,4-dienoyl-CoA reductase (NADPH) activity
C	0016491	molecular_function	oxidoreductase activity
C	0019166	molecular_function	trans-2-enoyl-CoA reductase (NADPH) activity
C	0033306	biological_process	phytol metabolic process
D	0005102	molecular_function	signaling receptor binding
D	0005739	cellular_component	mitochondrion
D	0005777	cellular_component	peroxisome
D	0005778	cellular_component	peroxisomal membrane
D	0005829	cellular_component	cytosol
D	0006633	biological_process	fatty acid biosynthetic process
D	0008670	molecular_function	2,4-dienoyl-CoA reductase (NADPH) activity
D	0016491	molecular_function	oxidoreductase activity
D	0019166	molecular_function	trans-2-enoyl-CoA reductase (NADPH) activity
D	0033306	biological_process	phytol metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 304

Chain	Residue
A	GLN17
A	LYS70
A	GLN71
A	ALA72

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 D 1001

Chain	Residue
D	HOH2056
D	HOH2086
D	HOH2088
D	THR28
D	GLY29
D	ILE30
D	GLY31
D	ASN107

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 2001

Chain	Residue
D	GLY29
D	SER206
D	GLN207
D	THR208

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 B 3001

Chain	Residue
B	SER49
B	ARG50
B	LYS51
B	ADE4002

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 4001

Chain	Residue
B	GLN17
B	LYS70
B	GLN71
B	ALA72
B	SER219

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ADE B 4002

Chain	Residue
B	SER49
B	ARG50
B	CYS79
B	ASN80
B	ILE81
B	GLY109
B	THR130
B	PO43001

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000250

Chain	Residue	Details
A	TYR179
B	TYR179
C	TYR179
D	TYR179

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	VAL23
B	VAL23
C	VAL23
D	VAL23

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q99MZ7

Chain	Residue	Details
A	LYS32
B	LYS32
C	LYS32
D	LYS32

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER49
B	SER49
C	SER49
D	SER49

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	TYR179
B	TYR179
C	TYR179
D	TYR179

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