1YUB

SOLUTION STRUCTURE OF AN RRNA METHYLTRANSFERASE (ERMAM) THAT CONFERS MACROLIDE-LINCOSAMIDE-STREPTOGRAMIN ANTIBIOTIC RESISTANCE, NMR, MINIMIZED AVERAGE STRUCTURE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000154	biological_process	rRNA modification
A	0000179	molecular_function	rRNA (adenine-N6,N6-)-dimethyltransferase activity
A	0003723	molecular_function	RNA binding
A	0005829	cellular_component	cytosol
A	0008168	molecular_function	methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0031167	biological_process	rRNA methylation
A	0032259	biological_process	methylation
A	0046677	biological_process	response to antibiotic
A	0052910	molecular_function	23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity

Functional Information from PROSITE/UniProt

site_id	PS01131
Number of Residues	28
Details	RRNA_A_DIMETH Ribosomal RNA adenine dimethylases signature. VYEiGTGkGhLTtklAkiskq...VtSIElD

Chain	Residue	Details
A	VAL33-ASP60

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01026

Chain	Residue	Details
A	ASN10
A	LEU12
A	GLY37
A	GLU58
A	ASP83
A	ASN100

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1qam

Chain	Residue	Details
A	GLU58
A	ASN100
A	GLY37

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