1YTA

Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000175	molecular_function	3'-5'-RNA exonuclease activity
A	0003676	molecular_function	nucleic acid binding
A	0004527	molecular_function	exonuclease activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006259	biological_process	DNA metabolic process
A	0006401	biological_process	RNA catabolic process
A	0008310	molecular_function	single-stranded DNA 3'-5' DNA exonuclease activity
A	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
A	0034611	molecular_function	oligoribonucleotidase activity
A	0046872	molecular_function	metal ion binding
B	0000175	molecular_function	3'-5'-RNA exonuclease activity
B	0003676	molecular_function	nucleic acid binding
B	0004527	molecular_function	exonuclease activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006259	biological_process	DNA metabolic process
B	0006401	biological_process	RNA catabolic process
B	0008310	molecular_function	single-stranded DNA 3'-5' DNA exonuclease activity
B	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
B	0034611	molecular_function	oligoribonucleotidase activity
B	0046872	molecular_function	metal ion binding
C	0000175	molecular_function	3'-5'-RNA exonuclease activity
C	0003676	molecular_function	nucleic acid binding
C	0004527	molecular_function	exonuclease activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006259	biological_process	DNA metabolic process
C	0006401	biological_process	RNA catabolic process
C	0008310	molecular_function	single-stranded DNA 3'-5' DNA exonuclease activity
C	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
C	0034611	molecular_function	oligoribonucleotidase activity
C	0046872	molecular_function	metal ion binding
D	0000175	molecular_function	3'-5'-RNA exonuclease activity
D	0003676	molecular_function	nucleic acid binding
D	0004527	molecular_function	exonuclease activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006259	biological_process	DNA metabolic process
D	0006401	biological_process	RNA catabolic process
D	0008310	molecular_function	single-stranded DNA 3'-5' DNA exonuclease activity
D	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
D	0034611	molecular_function	oligoribonucleotidase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FLC A 1001

Chain	Residue
A	ASN106
D	ARG63
A	SER107
A	SER134
A	LYS137
A	LYS153
A	HOH1045
A	HOH1055
B	TYR128
B	ARG129

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE FLC B 1002

Chain	Residue
A	TYR128
A	ARG129
B	ASN106
B	SER107
B	SER134
B	LYS137
B	LYS153
C	ARG63

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FLC C 1003

Chain	Residue
B	ALA67
C	ASN106
C	SER107
C	SER134
C	LYS137
C	LYS153
C	HOH1037
C	HOH1054
D	TYR128
D	ARG129

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FLC D 1004

Chain	Residue
A	ARG63
A	ALA67
C	TYR128
C	ARG129
D	ASN106
D	SER107
D	SER134
D	LYS137
D	LYS153

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FLC A 1005

Chain	Residue
A	GLU20
A	LYS117

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: ACT_SITE => ECO:0000255

Chain	Residue	Details
A	ARG129
B	ARG129
C	ARG129
D	ARG129

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
A	LEU12
A	MSE14
A	ILE163
B	LEU12
B	MSE14
B	ILE163
C	LEU12
C	MSE14
C	ILE163
D	LEU12
D	MSE14
D	ILE163

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