Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003756 | molecular_function | protein disulfide isomerase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0050451 | molecular_function | CoA-disulfide reductase (NADPH) activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0050661 | molecular_function | NADP binding |
| B | 0003756 | molecular_function | protein disulfide isomerase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0050451 | molecular_function | CoA-disulfide reductase (NADPH) activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 2001 |
| Chain | Residue |
| A | HOH3072 |
| A | HOH3090 |
| A | HOH3116 |
| B | HOH3075 |
| B | HOH3110 |
| B | HOH3133 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 2002 |
| Chain | Residue |
| A | HOH3439 |
| A | HOH3546 |
| A | HOH3313 |
| A | HOH3416 |
| A | HOH3433 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 2003 |
| Chain | Residue |
| A | HOH3188 |
| A | HOH3371 |
| A | HOH3601 |
| B | HOH3183 |
| B | HOH3251 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 3001 |
| Chain | Residue |
| A | TYR361 |
| B | ALA41 |
| B | CYS43 |
| B | COA442 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 3002 |
| Chain | Residue |
| A | ALA41 |
| A | CYS43 |
| A | COA441 |
| B | TYR361 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 3003 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 3004 |
| Chain | Residue |
| B | THR354 |
| B | LYS436 |
| B | HOH3208 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 3005 |
| Chain | Residue |
| A | ASN85 |
| A | GLU87 |
| A | ARG88 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 3006 |
| Chain | Residue |
| A | HOH3542 |
| B | ASN85 |
| B | GLU87 |
| B | ARG88 |
| site_id | BC1 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE COA A 441 |
| Chain | Residue |
| A | ALA14 |
| A | THR15 |
| A | SER18 |
| A | GLN19 |
| A | ARG22 |
| A | SER39 |
| A | PHE40 |
| A | ASN42 |
| A | CYS43 |
| A | ALA61 |
| A | LYS71 |
| A | ALA295 |
| A | HIS299 |
| A | FAD439 |
| A | CL3002 |
| A | HOH3136 |
| A | HOH3171 |
| A | HOH3259 |
| A | HOH3366 |
| A | HOH3371 |
| A | HOH3398 |
| A | HOH3440 |
| A | HOH3485 |
| A | HOH3510 |
| A | HOH3514 |
| A | HOH3523 |
| A | HOH3667 |
| A | HOH3685 |
| B | LYS427 |
| B | MET432 |
| B | TYR435 |
| B | LYS436 |
| site_id | BC2 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE COA B 442 |
| Chain | Residue |
| A | TYR419 |
| A | PRO426 |
| A | LYS427 |
| A | MET432 |
| A | TYR435 |
| A | CL3001 |
| B | VAL10 |
| B | ALA11 |
| B | ALA14 |
| B | THR15 |
| B | SER18 |
| B | GLN19 |
| B | ARG22 |
| B | SER39 |
| B | PHE40 |
| B | ASN42 |
| B | CYS43 |
| B | ALA61 |
| B | TYR62 |
| B | ARG70 |
| B | LYS71 |
| B | ALA295 |
| B | HIS299 |
| B | FAD440 |
| B | HOH3154 |
| B | HOH3320 |
| B | HOH3408 |
| B | HOH3413 |
| B | HOH3550 |
| B | HOH3631 |
| site_id | BC3 |
| Number of Residues | 39 |
| Details | BINDING SITE FOR RESIDUE FAD A 439 |
| Chain | Residue |
| A | VAL10 |
| A | ALA11 |
| A | GLY12 |
| A | PHE32 |
| A | GLU33 |
| A | LYS34 |
| A | ASP35 |
| A | ASN42 |
| A | CYS43 |
| A | HIS79 |
| A | GLU80 |
| A | VAL81 |
| A | SER112 |
| A | PRO113 |
| A | GLY114 |
| A | ARG131 |
| A | TYR158 |
| A | VAL159 |
| A | PHE245 |
| A | GLY276 |
| A | ASP277 |
| A | PRO293 |
| A | LEU294 |
| A | ALA295 |
| A | COA441 |
| A | HOH3006 |
| A | HOH3007 |
| A | HOH3009 |
| A | HOH3017 |
| A | HOH3019 |
| A | HOH3020 |
| A | HOH3037 |
| A | HOH3047 |
| A | HOH3058 |
| B | TYR419 |
| B | ALA420 |
| B | PRO421 |
| A | VAL7 |
| A | GLY8 |
| site_id | BC4 |
| Number of Residues | 40 |
| Details | BINDING SITE FOR RESIDUE FAD B 440 |
| Chain | Residue |
| A | TYR419 |
| A | ALA420 |
| A | PRO421 |
| B | VAL7 |
| B | GLY8 |
| B | VAL10 |
| B | ALA11 |
| B | GLY12 |
| B | PHE32 |
| B | GLU33 |
| B | LYS34 |
| B | ASP35 |
| B | ASN42 |
| B | CYS43 |
| B | HIS79 |
| B | GLU80 |
| B | VAL81 |
| B | SER112 |
| B | PRO113 |
| B | GLY114 |
| B | ARG131 |
| B | TYR158 |
| B | ASN242 |
| B | PHE245 |
| B | GLY276 |
| B | ASP277 |
| B | PRO293 |
| B | LEU294 |
| B | ALA295 |
| B | COA442 |
| B | HOH3007 |
| B | HOH3010 |
| B | HOH3011 |
| B | HOH3023 |
| B | HOH3025 |
| B | HOH3031 |
| B | HOH3034 |
| B | HOH3045 |
| B | HOH3052 |
| B | HOH3321 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Redox-active","evidences":[{"source":"PubMed","id":"10052943","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 88 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16981688","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
1YQZ
