1YQS
Inhibition of the R61 DD-Peptidase by N-benzoyl-beta-sultam
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004180 | molecular_function | carboxypeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008360 | biological_process | regulation of cell shape |
| A | 0009002 | molecular_function | serine-type D-Ala-D-Ala carboxypeptidase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE BSA A 400 |
| Chain | Residue |
| A | SER62 |
| A | HOH2253 |
| A | TYR159 |
| A | ARG285 |
| A | HIS298 |
| A | THR299 |
| A | GLY300 |
| A | THR301 |
| A | TYR308 |
| A | LEU332 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE BSA A 401 |
| Chain | Residue |
| A | ARG99 |
| A | THR116 |
| A | ASN117 |
| A | PHE120 |
| A | LEU214 |
| A | TYR306 |
| A | SER326 |
| A | ASN327 |
| A | HOH2085 |
| A | HOH2129 |
| A | HOH2344 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 500 |
| Chain | Residue |
| A | VAL204 |
| A | ILE205 |
| A | GLY207 |
| A | HIS209 |
| A | LYS346 |
| A | HOH2049 |
| A | HOH2217 |
| A | HOH2223 |
| A | HOH2340 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 502 |
| Chain | Residue |
| A | ASP45 |
| A | ARG50 |
| A | HIS209 |
| A | ASN211 |
| A | HOH2021 |
| A | HOH2026 |
| A | HOH2207 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"PubMed","id":"12215418","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12564922","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15581896","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12215418","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12564922","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15581896","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1ei5 |
| Chain | Residue | Details |
| A | HIS298 | |
| A | SER62 | |
| A | ASN161 | |
| A | LYS65 | |
| A | TYR159 |
