Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004252 | molecular_function | serine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| E | 0004252 | molecular_function | serine-type endopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| F | 0004252 | molecular_function | serine-type endopeptidase activity |
| F | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 E 1300 |
| Chain | Residue |
| E | TRP172 |
| E | SER218 |
| E | HOH1337 |
| E | HOH1348 |
| F | LYS175 |
| F | SO41301 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 F 1301 |
| Chain | Residue |
| F | TYR171 |
| F | TRP172 |
| F | SER217 |
| F | SER218 |
| F | HOH1352 |
| E | LYS175 |
| E | SO41300 |
| E | HOH1406 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1302 |
| Chain | Residue |
| C | LYS90 |
| C | SER96 |
| C | HOH1355 |
| D | ARG145 |
| D | HOH2355 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1303 |
| Chain | Residue |
| C | LYS90 |
| C | ASN91 |
| C | SER92 |
| C | HOH1344 |
| C | HOH1467 |
| E | TRP237 |
| E | HOH1378 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 2300 |
| Chain | Residue |
| D | ASN91 |
| D | SER92 |
| D | HOH2328 |
| D | HOH2370 |
| D | HOH2377 |
| F | TRP237 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC |
| Chain | Residue | Details |
| C | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SScmGDSGGPLV |
| Chain | Residue | Details |
| E | SER189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Charge relay system"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hja |
| Chain | Residue | Details |
| E | SER195 | |
| E | GLY193 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hja |
| Chain | Residue | Details |
| F | SER195 | |
| F | GLY193 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1hja |
| Chain | Residue | Details |
| C | ASP102 | |
| C | HIS57 | |
| E | SER195 | |
| E | GLY196 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1hja |
| Chain | Residue | Details |
| F | SER195 | |
| F | GLY196 | |
| D | ASP102 | |
| D | HIS57 | |
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 387 |
| Chain | Residue | Details |
| C | VAL60 | electrostatic stabiliser |
| C | THR62 | covalent catalysis |
| C | SER63 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 3 |
| Details | M-CSA 387 |
| Chain | Residue | Details |
| F | GLY193 | electrostatic stabiliser |
| F | SER195 | covalent catalysis |
| F | GLY196 | electrostatic stabiliser |
