1YON

Escherichia coli ketopantoate reductase in complex with 2-monophosphoadenosine-5'-diphosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0008677	molecular_function	2-dehydropantoate 2-reductase activity
A	0015940	biological_process	pantothenate biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0050661	molecular_function	NADP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	BINDING SITE FOR RESIDUE A2R A 501

Chain	Residue
A	GLY9
A	HIS120
A	LYS176
A	SER244
A	ASP248
A	ARG253
A	GLU256
A	HOH568
A	HOH610
A	HOH611
A	HOH613
A	ALA10
A	HOH654
A	HOH661
A	HOH669
A	HOH671
A	LEU11
A	THR70
A	LEU71
A	LYS72
A	HIS97
A	ASN98
A	THR118

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"11123955","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15966718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17229734","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17229734","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 17242510

Chain	Residue	Details
A	LYS176

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site_id	MCSA1
Number of Residues	1
Details	M-CSA 721

Chain	Residue	Details
A	LYS176	proton acceptor, proton donor

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