Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004713 | molecular_function | protein tyrosine kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE S03 A 601 |
Chain | Residue |
A | ALA295 |
A | LEU395 |
A | HOH651 |
B | THR525 |
A | LYS297 |
A | GLU312 |
A | ILE338 |
A | THR340 |
A | GLU341 |
A | MET343 |
A | SER347 |
A | ASP350 |
site_id | AC2 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE S03 B 602 |
Chain | Residue |
B | LEU275 |
B | ALA295 |
B | LYS297 |
B | ILE338 |
B | THR340 |
B | GLU341 |
B | MET343 |
B | ASP350 |
B | LEU395 |
B | ASP406 |
B | HOH659 |
B | HOH723 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 23 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGQGCFGEVWmGtwngttr...........VAIK |
Chain | Residue | Details |
A | LEU275-LYS297 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YVHrDLRAANILV |
Chain | Residue | Details |
A | TYR384-VAL396 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | LEU389 | |
B | LEU389 | |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | BINDING: |
Chain | Residue | Details |
A | GLY276 | |
A | THR298 | |
B | GLY276 | |
B | THR298 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | MOD_RES: Phosphotyrosine; by FAK2 => ECO:0000250 |
Chain | Residue | Details |
A | THR419 | |
B | THR419 | |
Chain | Residue | Details |
A | GLN530 | |
B | GLN530 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ASP388 | |
A | ALA392 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
B | ASP388 | |
B | ALA392 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ASP388 | |
A | ARG390 | |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
B | ASP388 | |
B | ARG390 | |
site_id | CSA5 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
A | ASP388 | |
A | ASN393 | |
A | ARG390 | |
site_id | CSA6 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
B | ASP388 | |
B | ASN393 | |
B | ARG390 | |