Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005509 | molecular_function | calcium ion binding |
A | 0005515 | molecular_function | protein binding |
A | 0005576 | cellular_component | extracellular region |
A | 0005615 | cellular_component | extracellular space |
A | 0006508 | biological_process | proteolysis |
A | 0007584 | biological_process | response to nutrient |
A | 0007586 | biological_process | digestion |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0030574 | biological_process | collagen catabolic process |
A | 0046872 | molecular_function | metal ion binding |
B | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 800 |
Chain | Residue |
A | GLU70 |
A | ASN72 |
A | VAL75 |
A | GLU77 |
A | GLU80 |
A | HOH526 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 B 990 |
Chain | Residue |
B | HOH664 |
B | LYS41 |
B | ARG42 |
B | HOH529 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 B 991 |
Chain | Residue |
B | ARG20 |
B | TYR35 |
B | ALA40 |
B | HOH639 |
B | HOH687 |
B | HOH705 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
Chain | Residue | Details |
A | VAL53-CYS58 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | SITE: Reactive bond for trypsin |
Chain | Residue | Details |
B | LYS15 | |
A | ASP102 | |
A | ALA195 | |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | BINDING: |
Chain | Residue | Details |
A | GLU70 | |
A | ASN72 | |
A | VAL75 | |
A | GLU80 | |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | SITE: Required for specificity => ECO:0000250 |
Chain | Residue | Details |
A | ASP189 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | HIS57 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ALA195 | |
A | GLY196 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ALA195 | |
A | GLY193 | |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | ALA195 | |
A | HIS57 | |
site_id | CSA5 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | ALA195 | |
A | GLY193 | |
A | HIS57 | |
site_id | CSA6 |
Number of Residues | 7 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | GLN192 | |
A | ASP102 | |
A | ALA195 | |
A | GLY193 | |
A | CYS191 | |
A | HIS57 | |
A | ASP194 | |