1YK0

structure of natriuretic peptide receptor-C complexed with atrial natriuretic peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
B	0016020	cellular_component	membrane
E	0005179	molecular_function	hormone activity
E	0005576	cellular_component	extracellular region

Functional Information from PROSITE/UniProt

site_id	PS00263
Number of Residues	17
Details	NATRIURETIC_PEPTIDE Natriuretic peptides signature. CFGgrmDRIgaqSglGC

Chain	Residue	Details
E	CYS7-CYS23

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site_id	PS00458
Number of Residues	18
Details	ANF_RECEPTORS Natriuretic peptides receptors signature. GPvCeYaAApVaRlasHW

Chain	Residue	Details
A	GLY88-TRP105

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Cleavage; by MME => ECO:0000269|PubMed:2972276

Chain	Residue	Details
E	CYS7
A	VAL90
A	CYS91
B	SER61
B	VAL90
B	CYS91

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:2528951

Chain	Residue	Details
E	SER6
B	ASN41

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site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine => ECO:0000269|PubMed:11533490, ECO:0000269|PubMed:16870210, ECO:0000269|PubMed:7727388

Chain	Residue	Details
A	ASN248
B	ASN248

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:11533490, ECO:0000269|PubMed:16870210, ECO:0000269|PubMed:7727388

Chain	Residue	Details
A	ASN349
B	ASN349

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