1YIQ

Molecular cloning and structural analysis of quinohemoprotein alcohol dehydrogenase ADHIIG from Pseudomonas putida HK5. Compariison to the other quinohemoprotein alcohol dehydrogenase ADHIIB found in the same microorganism.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0009055	molecular_function	electron transfer activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
A	0020037	molecular_function	heme binding
A	0022900	biological_process	electron transport chain
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding
A	0050039	molecular_function	lactaldehyde reductase (NADPH) activity
A	0070968	molecular_function	pyrroloquinoline quinone binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 802

Chain	Residue
A	GLU178
A	ASN255
A	ASP300
A	PQQ801
A	PGR803

---

site_id	AC2
Number of Residues	24
Details	BINDING SITE FOR RESIDUE PQQ A 801

Chain	Residue
A	ARG115
A	THR160
A	GLY175
A	GLY176
A	ALA177
A	GLU178
A	THR235
A	TRP237
A	ASN255
A	ASP300
A	LYS327
A	TRP386
A	ASP390
A	TRP391
A	PHE477
A	ALA542
A	CA802
A	PGR803
A	HOH1079
A	HOH1108
A	GLU63
A	CYS109
A	CYS110
A	VAL113

---

site_id	AC3
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEC A 901

Chain	Residue
A	ARG60
A	GLY106
A	TYR605
A	CYS606
A	GLN608
A	CYS609
A	HIS610
A	LEU623
A	LEU626
A	LYS630
A	LEU638
A	ARG642
A	ASP645
A	GLY646
A	MET647
A	PHE650
A	PHE654
A	HOH1088
A	HOH1303
A	HOH1373

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PGR A 803

Chain	Residue
A	CYS110
A	GLU178
A	ASP300
A	TRP386
A	ALA542
A	PQQ801
A	CA802
A	HOH1271

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PGR A 804

Chain	Residue
A	GLU441
A	ILE595
A	TYR665
A	LYS668

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PGR A 805

Chain	Residue
A	LEU552
A	ARG579
A	SER616
A	ASP622
A	ARG624
A	LYS625
A	HOH1201

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:16061256

Chain	Residue	Details
A	ASP300

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q46444

Chain	Residue	Details
A	GLU63
A	ALA542

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:16061256, ECO:0007744|PDB:1YIQ

Chain	Residue	Details
A	ARG115
A	ASP390
A	THR160
A	GLY176
A	GLU178
A	THR235
A	ASN255
A	ASP300
A	LYS327
A	TRP386

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: covalent => ECO:0000269|PubMed:16061256, ECO:0007744|PDB:1YIQ

Chain	Residue	Details
A	CYS606
A	CYS609

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: axial binding residue => ECO:0000269|PubMed:16061256, ECO:0007744|PDB:1YIQ

Chain	Residue	Details
A	HIS610
A	MET647

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1g72

Chain	Residue	Details
A	ASP300

---