Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003908 | molecular_function | methylated-DNA-[protein]-cysteine S-methyltransferase activity |
| A | 0006281 | biological_process | DNA repair |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003908 | molecular_function | methylated-DNA-[protein]-cysteine S-methyltransferase activity |
| B | 0006281 | biological_process | DNA repair |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0003908 | molecular_function | methylated-DNA-[protein]-cysteine S-methyltransferase activity |
| C | 0006281 | biological_process | DNA repair |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 301 |
| Chain | Residue |
| A | CYS5 |
| A | MET7 |
| A | CYS24 |
| A | HIS29 |
| A | HIS85 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 302 |
| Chain | Residue |
| C | CYS5 |
| C | CYS24 |
| C | HIS29 |
| C | HIS85 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 303 |
| Chain | Residue |
| B | CYS5 |
| B | MET7 |
| B | CYS24 |
| B | HIS29 |
| B | HIS85 |
Functional Information from PROSITE/UniProt
| site_id | PS00374 |
| Number of Residues | 7 |
| Details | MGMT Methylated-DNA--protein-cysteine methyltransferase active site. IPCHRVV |
| Chain | Residue | Details |
| A | ILE143-VAL149 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. GLHEIKLLGKG |
| Chain | Residue | Details |
| A | GLY27-GLY37 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Nucleophile; methyl group acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10747039","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15964013","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1eh6 |
| Chain | Residue | Details |
| A | GLU172 | |
| A | CYS145 | |
| A | ASN137 | |
| A | HIS146 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1eh6 |
| Chain | Residue | Details |
| B | GLU172 | |
| B | CYS145 | |
| B | ASN137 | |
| B | HIS146 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1eh6 |
| Chain | Residue | Details |
| C | GLU172 | |
| C | CYS145 | |
| C | ASN137 | |
| C | HIS146 | |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 251 |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 251 |
| site_id | MCSA3 |
| Number of Residues | 5 |
| Details | M-CSA 251 |
