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1YCK

Crystal structure of human peptidoglycan recognition protein (PGRP-S)

Functional Information from GO Data
ChainGOidnamespacecontents
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006955biological_processimmune response
A0007165biological_processsignal transduction
A0008270molecular_functionzinc ion binding
A0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
A0009253biological_processpeptidoglycan catabolic process
A0009617biological_processresponse to bacterium
A0016019molecular_functionpeptidoglycan immune receptor activity
A0016045biological_processdetection of bacterium
A0030544molecular_functionHsp70 protein binding
A0031640biological_processkilling of cells of another organism
A0032689biological_processnegative regulation of type II interferon production
A0032827biological_processnegative regulation of natural killer cell differentiation involved in immune response
A0035580cellular_componentspecific granule lumen
A0042742biological_processdefense response to bacterium
A0042834molecular_functionpeptidoglycan binding
A0045087biological_processinnate immune response
A0048018molecular_functionreceptor ligand activity
A0050728biological_processnegative regulation of inflammatory response
A0050830biological_processdefense response to Gram-positive bacterium
A0051701biological_processbiological process involved in interaction with host
A0060090molecular_functionmolecular adaptor activity
A0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
A0070062cellular_componentextracellular exosome
A0097013cellular_componentphagocytic vesicle lumen
A1904724cellular_componenttertiary granule lumen
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Pyrrolidone carboxylic acid => ECO:0000250|UniProtKB:Q8SPP7
ChainResidueDetails
AGLN1

site_idSWS_FT_FI2
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN91

227111

PDB entries from 2024-11-06

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